Results from patients with thrombocytopenia
Case . | Platelet count (× 109/L) . | Direct PIFT T/C ratio* . | OD values . | |||
---|---|---|---|---|---|---|
Direct MAIPA† . | Indirect MAIPA‡ . | |||||
Control . | Patient . | Control . | Patient . | |||
1 | 2 | 3.6 | 0.13 | 1.85 | 0.12 | 0.151-153 |
2 | 6 | 6.8 | 0.09 | 0.23 | 0.01 | 0.10 |
3 | 7 | 22.8 | nt | nt | 0.01 | 0.21 |
4 | 12 | nt | nt | nt | 0.01 | 0.21 |
5 | 35 | 8.8 | 0.01 | 1.63 | 0.02 | 0.08 |
6 | 58 | 3.9 | 0.13 | 1.07 | 0.12 | 0.29 |
7 | 60 | 1.9 | 0.03 | > 3.5 | 0.02 | 0.26 |
8 | na | positive | nt | nt | 0.23 | 0.60 |
9 | na | positive | nt | nt | 0.02 | 0.18 |
10 | na | na | nt | nt | 0.09 | 0.151-153 |
0.091-159 | 0.541-159 |
Case . | Platelet count (× 109/L) . | Direct PIFT T/C ratio* . | OD values . | |||
---|---|---|---|---|---|---|
Direct MAIPA† . | Indirect MAIPA‡ . | |||||
Control . | Patient . | Control . | Patient . | |||
1 | 2 | 3.6 | 0.13 | 1.85 | 0.12 | 0.151-153 |
2 | 6 | 6.8 | 0.09 | 0.23 | 0.01 | 0.10 |
3 | 7 | 22.8 | nt | nt | 0.01 | 0.21 |
4 | 12 | nt | nt | nt | 0.01 | 0.21 |
5 | 35 | 8.8 | 0.01 | 1.63 | 0.02 | 0.08 |
6 | 58 | 3.9 | 0.13 | 1.07 | 0.12 | 0.29 |
7 | 60 | 1.9 | 0.03 | > 3.5 | 0.02 | 0.26 |
8 | na | positive | nt | nt | 0.23 | 0.60 |
9 | na | positive | nt | nt | 0.02 | 0.18 |
10 | na | na | nt | nt | 0.09 | 0.151-153 |
0.091-159 | 0.541-159 |
Flow cytometry test results as a ratio of the test result (T) compared with the control (C). Samples 8 and 9 were tested by microscopy.
Results from control healthy donor platelets and patient's own platelets tested in parallel, using SW16 anti-GPV as capture mAb.
Average result from testing at least 3 cells previously incubated with the blood group AB control sera and patient's serum tested in parallel, using SW16 anti-GPV as capture mAb.
Result not above cut-off of twice the control result.
Autoantibodies were eluted from the patient's platelets and tested by MAIPA.
na, not available, archive samples referred to in the text; nt, not tested.