Characteristics of patients experiencing acute no-reflow in the course of percutaneous coronary interventions
| Patient . | Age/sex . | Culprit vessel . | Circumstance of NR . | Initial TIMI flow grade . | TF antigen, pg/mL NR/R . | Increase of TF antigen after freeze thawing of NR plasma, pg/mL . | Timing (min)† . |
|---|---|---|---|---|---|---|---|
| 1 | 64/f | proximal LAD | dissection after PTCA | 3 | 180.95/119.51 | 72.24 | 5/50 |
| 2 | 50/m | high-grade mid RCA | unstable angina | 1 | 124.45/79.32 | 24.05 | 120/200 |
| 3 | 47/m | proximal LAD | directional atherectomy | 3 | 119.55/50.73 | 13.76 | 35/60 |
| 4 | 52/m | proximal RCA | unstable angina | 2 | 38.50/17.65 | 10.29 | 15/70 |
| 5 | 76/f | proximal CX | CX thrombosis during LAD PTCA | 0 | 269.45/90.46 | 194.90 | 30/100 |
| 6 | 52/m | proximal RCA | unstable angina | 0 | 144.23/75.82 | 55.81 | 150/200 |
| 7 | 71/m | proximal LAD | distal dissection after stenting | 2 | 88.76/79.42 | 19.80 | 20/60 |
| 8 | 60/m | mid RCA | thrombus dislodged by guide wire | 2 | 158.08/* | 29.97 | 120/180 |
| 9 | 86/f | proximal LAD | unstable angina | 0 | 269.45/* | 89.50 | 120/180 |
| 10 | 60/f | proximal LAD | unstable angina | 1 | 203.44/* | 10.31 | 180/250 |
| 11 | 53/m | mid LAD | dissection after PTCA | 2 | 63.48/* | 15.16 | 15/45 |
| 12 | 78/m | CX vein graft | acute MI | 1 | 595.25/* | 18.55 | 180/220 |
| 13 | 44/m | proximal LAD | acute MI | 0 | 269.75/* | 134.50 | 120/260 |
| Patient . | Age/sex . | Culprit vessel . | Circumstance of NR . | Initial TIMI flow grade . | TF antigen, pg/mL NR/R . | Increase of TF antigen after freeze thawing of NR plasma, pg/mL . | Timing (min)† . |
|---|---|---|---|---|---|---|---|
| 1 | 64/f | proximal LAD | dissection after PTCA | 3 | 180.95/119.51 | 72.24 | 5/50 |
| 2 | 50/m | high-grade mid RCA | unstable angina | 1 | 124.45/79.32 | 24.05 | 120/200 |
| 3 | 47/m | proximal LAD | directional atherectomy | 3 | 119.55/50.73 | 13.76 | 35/60 |
| 4 | 52/m | proximal RCA | unstable angina | 2 | 38.50/17.65 | 10.29 | 15/70 |
| 5 | 76/f | proximal CX | CX thrombosis during LAD PTCA | 0 | 269.45/90.46 | 194.90 | 30/100 |
| 6 | 52/m | proximal RCA | unstable angina | 0 | 144.23/75.82 | 55.81 | 150/200 |
| 7 | 71/m | proximal LAD | distal dissection after stenting | 2 | 88.76/79.42 | 19.80 | 20/60 |
| 8 | 60/m | mid RCA | thrombus dislodged by guide wire | 2 | 158.08/* | 29.97 | 120/180 |
| 9 | 86/f | proximal LAD | unstable angina | 0 | 269.45/* | 89.50 | 120/180 |
| 10 | 60/f | proximal LAD | unstable angina | 1 | 203.44/* | 10.31 | 180/250 |
| 11 | 53/m | mid LAD | dissection after PTCA | 2 | 63.48/* | 15.16 | 15/45 |
| 12 | 78/m | CX vein graft | acute MI | 1 | 595.25/* | 18.55 | 180/220 |
| 13 | 44/m | proximal LAD | acute MI | 0 | 269.75/* | 134.50 | 120/260 |
Initial TIMI flow grade refers to the first angiogram of the target vessel. PTCA indicates percutaneous transluminal coronary angioplasty; CX, circumflex coronary artery. Other abbreviations are explained in Table 1.
Patients in whom a second blood sample was not available because of persistent NR.
Time interval from the onset of chest pain/NR to the first blood harvest/interval from the onset of chest pain/NR to the end of the percutaneous intervention and second blood draw. In patients with impaired flow at the beginning of the procedure, the onset of chest pain was used for the calculation of the time intervals because the TF–up-regulating process could have started prior to angiographic NR.