Previously published results detecting leukemic clones at birth from newborn screening cards
| . | Age at diagnosis . | Detected at birth . | ALL subtype . |
|---|---|---|---|
| Translocation breakpoint fusion sequence used as leukemic clone marker | |||
| Gale et al17; Marker: t(4;11) | 5 mo | + | BP-ALL |
| 6 mo | + | BP-ALL | |
| 24 mo | + | BP-ALL | |
| Wiemels et al18; Marker: t(12;21) | 25 mo | + | BP-ALL |
| 34 mo | + | BP-ALL | |
| 39 mo | + | BP-ALL | |
| 40 mo | − | BP-ALL | |
| 41 mo | − | BP-ALL | |
| 42 mo | + | BP-ALL | |
| 47 mo | − | BP-ALL | |
| 51 mo | + | BP-ALL | |
| 61 mo | + | BP-ALL | |
| Clonal IgH/TcR gene rearrangement used as leukemic clone marker | |||
| Fasching et al19; Marker: IgH/TcR | 6 mo | + | t(4;11) |
| 12 mo | + | t(4;11) | |
| 56 mo | + | BP-ALL | |
| 25 mo | + | T-ALL | |
| 26 mo | + | T-ALL | |
| Yagi et al20; Marker: IgH/TcR | 14 d | + | t(4;11) |
| 2 mo | + | t(4;11) | |
| 2 y | + | BP-ALL | |
| 2.2 y | + | BP-ALL | |
| 1.5 y | − | BP-ALL | |
| 9 y | − | BP-ALL | |
| 2 y | − | BP-ALL |
| . | Age at diagnosis . | Detected at birth . | ALL subtype . |
|---|---|---|---|
| Translocation breakpoint fusion sequence used as leukemic clone marker | |||
| Gale et al17; Marker: t(4;11) | 5 mo | + | BP-ALL |
| 6 mo | + | BP-ALL | |
| 24 mo | + | BP-ALL | |
| Wiemels et al18; Marker: t(12;21) | 25 mo | + | BP-ALL |
| 34 mo | + | BP-ALL | |
| 39 mo | + | BP-ALL | |
| 40 mo | − | BP-ALL | |
| 41 mo | − | BP-ALL | |
| 42 mo | + | BP-ALL | |
| 47 mo | − | BP-ALL | |
| 51 mo | + | BP-ALL | |
| 61 mo | + | BP-ALL | |
| Clonal IgH/TcR gene rearrangement used as leukemic clone marker | |||
| Fasching et al19; Marker: IgH/TcR | 6 mo | + | t(4;11) |
| 12 mo | + | t(4;11) | |
| 56 mo | + | BP-ALL | |
| 25 mo | + | T-ALL | |
| 26 mo | + | T-ALL | |
| Yagi et al20; Marker: IgH/TcR | 14 d | + | t(4;11) |
| 2 mo | + | t(4;11) | |
| 2 y | + | BP-ALL | |
| 2.2 y | + | BP-ALL | |
| 1.5 y | − | BP-ALL | |
| 9 y | − | BP-ALL | |
| 2 y | − | BP-ALL |
BP-ALL indicates B-precursor acute lymphoblastic leukemia; TcR, T-cell receptor.