Patient characteristics and results
| Patient . | Sex . | Age at diagnosis . | Race . | WBC (/μL) . | Karyotype . | Leukemic clone detected on newborn card . |
|---|---|---|---|---|---|---|
| 1 | M | 18 mo | W | 4 000 | DNA index 1.13 | + |
| 2 | M | 25 mo | AA | 34 000 | 46,XY[8] | + |
| 3 | F | 27 mo | W | 32 100 | 51-52,XX,+ X,+ 6,+ 14,+ 18,+ 21,+ 21[13]/46,XX[8] | + |
| 4 | M | 30 mo | W | 36 900 | 47,XY,+ 21[10]/46,XY[22] | − |
| 5 | F | 33 mo | W | 9 400 | 48,XX,+ X,+ 21[17]/46,XX[17] | + |
| 6 | F | 34 mo | W | 4 400 | 56,XX,+ X,+ 4,+ 10,+ 14,+ 14,+ 18,+ 21,+ 22,+ mar,+ mar[1]/46,XX[19]; DNA index 1.20 | + |
| 7 | M | 35 mo | AA | 8 200 | 46,XY[29] (t(12;21) detected by FISH) | + |
| 8 | M | 42 mo | Asian | 8 500 | 55,XY,+ X,+ 4,+ 6,+ 9,+ 10,+ 14,+ 15,+ 21,+ 21[11]/46,XY[9] | + |
| 9 | F | 46 mo | W | 2 900 | 46,XX[22] | − |
| 10 | F | 4 y | W | 50 500 | 46,XX[21] | − |
| 11 | F | 4 y | W | 3 200 | 47,XX,t(10;12)(q22;p12),+ der(10)t(10;12)(q22;p12)[16]/46,XX[9] | − |
| 12 | M | 5 y | W | 5 700 | DNA index > 1.16 | + |
| 13 | F | 8 y | AA | 12 500 | 46,XX,del(6)(q15q23)[17]/46,XX[10] | + |
| 14 | M | 9 y | W | 2 300 | 55-57[4]/46,XY[23] | + |
| 15 | M | 9 y | W | 33 000 | 47,XY,+ 21[32] (Down syndrome) | − |
| 16 | M | 10 y | AA | 70 300 | 47,XY,+ X,t(4;11)(q21;q23),der(9;14)(q10;q10)[19]/46,XY[1] | + |
| 17 | F | 13 y | W | 46 400 | 46,XX,t(1;19)(q23;p13)[4]/46,idem,add(9)(p22)[3]/46,XX[3] | + |
| Patient . | Sex . | Age at diagnosis . | Race . | WBC (/μL) . | Karyotype . | Leukemic clone detected on newborn card . |
|---|---|---|---|---|---|---|
| 1 | M | 18 mo | W | 4 000 | DNA index 1.13 | + |
| 2 | M | 25 mo | AA | 34 000 | 46,XY[8] | + |
| 3 | F | 27 mo | W | 32 100 | 51-52,XX,+ X,+ 6,+ 14,+ 18,+ 21,+ 21[13]/46,XX[8] | + |
| 4 | M | 30 mo | W | 36 900 | 47,XY,+ 21[10]/46,XY[22] | − |
| 5 | F | 33 mo | W | 9 400 | 48,XX,+ X,+ 21[17]/46,XX[17] | + |
| 6 | F | 34 mo | W | 4 400 | 56,XX,+ X,+ 4,+ 10,+ 14,+ 14,+ 18,+ 21,+ 22,+ mar,+ mar[1]/46,XX[19]; DNA index 1.20 | + |
| 7 | M | 35 mo | AA | 8 200 | 46,XY[29] (t(12;21) detected by FISH) | + |
| 8 | M | 42 mo | Asian | 8 500 | 55,XY,+ X,+ 4,+ 6,+ 9,+ 10,+ 14,+ 15,+ 21,+ 21[11]/46,XY[9] | + |
| 9 | F | 46 mo | W | 2 900 | 46,XX[22] | − |
| 10 | F | 4 y | W | 50 500 | 46,XX[21] | − |
| 11 | F | 4 y | W | 3 200 | 47,XX,t(10;12)(q22;p12),+ der(10)t(10;12)(q22;p12)[16]/46,XX[9] | − |
| 12 | M | 5 y | W | 5 700 | DNA index > 1.16 | + |
| 13 | F | 8 y | AA | 12 500 | 46,XX,del(6)(q15q23)[17]/46,XX[10] | + |
| 14 | M | 9 y | W | 2 300 | 55-57[4]/46,XY[23] | + |
| 15 | M | 9 y | W | 33 000 | 47,XY,+ 21[32] (Down syndrome) | − |
| 16 | M | 10 y | AA | 70 300 | 47,XY,+ X,t(4;11)(q21;q23),der(9;14)(q10;q10)[19]/46,XY[1] | + |
| 17 | F | 13 y | W | 46 400 | 46,XX,t(1;19)(q23;p13)[4]/46,idem,add(9)(p22)[3]/46,XX[3] | + |
W indicates white; AA, African American; FISH, fluorescence in situ hybridization.