Disappearance of WT1 antibodies in leukemia patients in continuous complete remission
| Patient . | Disease . | WT1 antibody levels (densitometric units) . | Treatment . | Patients' conditions . | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| IgM . | IgG . | Time from end of treatment (y) . | Immunosuppression therapy . | Serum immunoglobulins . | |||||||
| At diagnosis . | In CCR . | At diagnosis . | In CCR . | IgM (52-270)3-150 . | IgG (880-1800) . | IgA (126-517) . | |||||
| 88 | AML | < 600 | < 600 | 989 | < 500 | Allo-BMT | 3.8 | (−) | 129 | 1077 | 145 |
| 95 | AML | 772 | < 600 | 794 | < 500 | Chemotherapy | 1.9 | (−) | 59 | 1140 | 120 |
| 5 | AML | 1477 | < 600 | 754 | < 500 | Chemotherapy | 2.3 | (−) | 58 | 1120 | 150 |
| 2 | AML | 1283 | < 600 | 1900 | < 500 | Allo-BMT | 2.0 | (−) | 69 | 1320 | 121 |
| Patient . | Disease . | WT1 antibody levels (densitometric units) . | Treatment . | Patients' conditions . | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| IgM . | IgG . | Time from end of treatment (y) . | Immunosuppression therapy . | Serum immunoglobulins . | |||||||
| At diagnosis . | In CCR . | At diagnosis . | In CCR . | IgM (52-270)3-150 . | IgG (880-1800) . | IgA (126-517) . | |||||
| 88 | AML | < 600 | < 600 | 989 | < 500 | Allo-BMT | 3.8 | (−) | 129 | 1077 | 145 |
| 95 | AML | 772 | < 600 | 794 | < 500 | Chemotherapy | 1.9 | (−) | 59 | 1140 | 120 |
| 5 | AML | 1477 | < 600 | 754 | < 500 | Chemotherapy | 2.3 | (−) | 58 | 1120 | 150 |
| 2 | AML | 1283 | < 600 | 1900 | < 500 | Allo-BMT | 2.0 | (−) | 69 | 1320 | 121 |
Patient conditions are shown when WT1 antibody levels were measured in CCR.
Number in parentheses represents normal range (mg/dL). CCR, persistent complete remission without relapse.