Sequential analysis of p16INK4aimmunocytochemistry in patients with acute lymphoblastic leukemia
| Patient no. . | Immunophenotype . | Positive leukemic cells by p16INK4a ICC, % . | |||
|---|---|---|---|---|---|
| Diagnosis . | First relapse . | Second relapse . | Third relapse . | ||
| I101 | B | ND | 80 | 95 | 100 |
| I102 | B | ND | 90 | 0 | — |
| I103 | B | ND | 100 | 0 | — |
| I104 | B | 70 | 100 | — | — |
| I105 | B | 100 | 25 | — | — |
| I106 | AUL | 3 | 2 | — | — |
| I107 | T | 0 | 1 | 0 | 0 |
| I108 | B | ND | 100 | ND | 100 |
| I109 | T | 75 | 40 | — | |
| I110 | B | 2 | 2 | — | — |
| I111 | B | 16 | 100 | — | — |
| I112 | B | 95 | 20 | — | — |
| I113 | AUL | 100 | 30 | — | — |
| I114 | T | ND | 2 | 0 | — |
| I115 | B | 1 | 1 | ND | — |
| I116 | B | ND | 1 | 0 | — |
| I117 | B | 100 | 70 | — | — |
| I118 | T | 0 | 1 | — | — |
| I119 | B | 80 | 1 | 0 | — |
| I120 | B | 2.5 | 16 | — | — |
| I121 | T | ND | 40 | — | — |
| I122 | B | ND | 35 | — | — |
| I123 | B | ND | 25 | — | — |
| I124 | B | ND | 50 | — | — |
| I125 | B | ND | 100 | — | — |
| I125 | AUL | ND | 100 | — | — |
| I127 | B | ND | 1 | — | — |
| I128 | B | ND | 2 | — | — |
| I129 | T | ND | 1 | — | — |
| I130 | B | ND | 35 | — | — |
| I131 | B | ND | 7 | — | — |
| Patient no. . | Immunophenotype . | Positive leukemic cells by p16INK4a ICC, % . | |||
|---|---|---|---|---|---|
| Diagnosis . | First relapse . | Second relapse . | Third relapse . | ||
| I101 | B | ND | 80 | 95 | 100 |
| I102 | B | ND | 90 | 0 | — |
| I103 | B | ND | 100 | 0 | — |
| I104 | B | 70 | 100 | — | — |
| I105 | B | 100 | 25 | — | — |
| I106 | AUL | 3 | 2 | — | — |
| I107 | T | 0 | 1 | 0 | 0 |
| I108 | B | ND | 100 | ND | 100 |
| I109 | T | 75 | 40 | — | |
| I110 | B | 2 | 2 | — | — |
| I111 | B | 16 | 100 | — | — |
| I112 | B | 95 | 20 | — | — |
| I113 | AUL | 100 | 30 | — | — |
| I114 | T | ND | 2 | 0 | — |
| I115 | B | 1 | 1 | ND | — |
| I116 | B | ND | 1 | 0 | — |
| I117 | B | 100 | 70 | — | — |
| I118 | T | 0 | 1 | — | — |
| I119 | B | 80 | 1 | 0 | — |
| I120 | B | 2.5 | 16 | — | — |
| I121 | T | ND | 40 | — | — |
| I122 | B | ND | 35 | — | — |
| I123 | B | ND | 25 | — | — |
| I124 | B | ND | 50 | — | — |
| I125 | B | ND | 100 | — | — |
| I125 | AUL | ND | 100 | — | — |
| I127 | B | ND | 1 | — | — |
| I128 | B | ND | 2 | — | — |
| I129 | T | ND | 1 | — | — |
| I130 | B | ND | 35 | — | — |
| I131 | B | ND | 7 | — | — |
ICC indicates immunocytochemistry; AUL, acute undifferentiated leukemia; ND, not done.