Table 3. Allele frequency of 10 factor... | American Society of Hematology

Table 3.

Allele frequency of 10 factor XI intragenic polymorphisms in French Basque controls and carriers of Cys38Arg mutation

Polymorphism^3-151	Controls		Carriers of Cys38Arg^3-150		P	Founder haplotype
Polymorphism^3-151	No. alleles	Frequency of bold-faced allele, %	No. alleles	Frequency of bold-faced allele, %	P	Founder haplotype
Intron A
−231C > T	82	77	20	75	NS	C
−138C >A	56	39	20	80	.002	A
Intron B, 1, 2, 3, 4	88	0	20	55	<.0001	1
Exon 5, 472C > T	84	93	20	100	NS	C
Intron E, −431 1, 2	62	65	18	78	NS	1
Exon 8, 844A > G	90	92	20	100	NS	A
Exon 11, 1234T > C	90	90	20	95	NS	T
Intron M, 1, 2, 3, 4	90	75	20	80	NS	3
Exon 15
1855G > T	80	91	20	95	NS	G
1882G > A	80	91	20	95	NS	G

Polymorphism^3-151	Controls		Carriers of Cys38Arg^3-150		P	Founder haplotype
Polymorphism^3-151	No. alleles	Frequency of bold-faced allele, %	No. alleles	Frequency of bold-faced allele, %	P	Founder haplotype
Intron A
−231C > T	82	77	20	75	NS	C
−138C >A	56	39	20	80	.002	A
Intron B, 1, 2, 3, 4	88	0	20	55	<.0001	1
Exon 5, 472C > T	84	93	20	100	NS	C
Intron E, −431 1, 2	62	65	18	78	NS	1
Exon 8, 844A > G	90	92	20	100	NS	A
Exon 11, 1234T > C	90	90	20	95	NS	T
Intron M, 1, 2, 3, 4	90	75	20	80	NS	3
Exon 15
1855G > T	80	91	20	95	NS	G
1882G > A	80	91	20	95	NS	G

NS indicates not statistically significant.

One homozygote, 1 compound heterozygote, and 8 heterozygotes.

The allele appearing in bold in each polymorphism in this column is the allele whose frequency is measured in 2 later columns.