Table 1. Molecular composition of α 1 m... | American Society of Hematology

Table 1.

Molecular composition of α₁m before and after cleavage by erythrocyte membranes and purified oxyhemoglobin

Source of α₁m	N-terminus		C-terminus		−SH group^*		Carbohydrates		Chromophore
Source of α₁m	Before	After	Before	After	Before	After	Before	After	Before	After
Plasma	G₁PVP …	G₁PVP …	… PEPILIPR₁₈₃	… PEPI₁₇₉	+	+	3	3	+	+++^†
IgA-α₁m	G₁PVP …	G₁PVP …	… PEPILIPR₁₈₃	… PEPI₁₇₉	0	+	nd	3	−	+++

Source of α₁m	N-terminus		C-terminus		−SH group^*		Carbohydrates		Chromophore
Source of α₁m	Before	After	Before	After	Before	After	Before	After	Before	After
Plasma	G₁PVP …	G₁PVP …	… PEPILIPR₁₈₃	… PEPI₁₇₉	+	+	3	3	+	+++^†
IgA-α₁m	G₁PVP …	G₁PVP …	… PEPILIPR₁₈₃	… PEPI₁₇₉	0	+	nd	3	−	+++

nd indicates not determined.

Free thiol groups were determined as absent (0) or present (+) before and after cleavage by erythrocyte membranes by alkylation with [¹⁴C]iodoacetamide.

†

The amount of chromophore was estimated by absorbance spectrum analysis and is graded from − to +++.

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