Previous major publications of CML in BT
| Author . | No. . | Overall response, % . | Median survival, mo . | Prognostic factors . |
|---|---|---|---|---|
| Coleman et al, 19808 | 202 | 34 | 3 | Response to therapy |
| Kantarjian et al, 198726 | 242 | 36 | 4.5 | Hemoglobin, platelets, BM blasts, type of BT, clonal evolution |
| Anger et al, 19886 | 69 | 40 | 2.5 | Clonal evolution, type of BT, BM blasts + promyelocytes, response to therapy |
| Derderian et al, 199314 | 296 | 20 | 3 | Type of BT |
| (LBC-68) | (49) | (9) | ||
| Griesshammer et al, 199629 | 90 | 29 | 2.8 | Response to therapy, presence of trisomy 8 |
| Sacchi et al, 19991 | 162 | 22 | 5.5 | Decitabine therapy particularly in older patients |
| Present study | 78 | 46 | 8.2 | Cytogenetic evolution, PB blasts |
| Author . | No. . | Overall response, % . | Median survival, mo . | Prognostic factors . |
|---|---|---|---|---|
| Coleman et al, 19808 | 202 | 34 | 3 | Response to therapy |
| Kantarjian et al, 198726 | 242 | 36 | 4.5 | Hemoglobin, platelets, BM blasts, type of BT, clonal evolution |
| Anger et al, 19886 | 69 | 40 | 2.5 | Clonal evolution, type of BT, BM blasts + promyelocytes, response to therapy |
| Derderian et al, 199314 | 296 | 20 | 3 | Type of BT |
| (LBC-68) | (49) | (9) | ||
| Griesshammer et al, 199629 | 90 | 29 | 2.8 | Response to therapy, presence of trisomy 8 |
| Sacchi et al, 19991 | 162 | 22 | 5.5 | Decitabine therapy particularly in older patients |
| Present study | 78 | 46 | 8.2 | Cytogenetic evolution, PB blasts |
LBC indicates lymphoid blastic crisis.