Chimerism in different cell subsets in the recipients of 2 major histocompatibility complex-mismatched allogeneic T-cell-depleted bone marrow cells
. | CD4+ T cells* . | CD8+ T cells* . | B cells* . | Myeloid cells* . | NKs† . | DCs† . |
---|---|---|---|---|---|---|
C57BL/6-derived | 26 ± 15 | 32 ± 18 | 17 ± 16 | 11 ± 1 | 41 ± 30 | 37 ± 29 |
SJL/J-derived | 40 ± 35 | 40 ± 34 | 79 ± 14 | 79 ± 7 | 58 ± 30 | 56 ± 30 |
BALB/c-derived | 33 ± 20 | 29 ± 18 | 3 ± 5 | 8 ± 6 | 0 ± 0 | 4 ± 3 |
. | CD4+ T cells* . | CD8+ T cells* . | B cells* . | Myeloid cells* . | NKs† . | DCs† . |
---|---|---|---|---|---|---|
C57BL/6-derived | 26 ± 15 | 32 ± 18 | 17 ± 16 | 11 ± 1 | 41 ± 30 | 37 ± 29 |
SJL/J-derived | 40 ± 35 | 40 ± 34 | 79 ± 14 | 79 ± 7 | 58 ± 30 | 56 ± 30 |
BALB/c-derived | 33 ± 20 | 29 ± 18 | 3 ± 5 | 8 ± 6 | 0 ± 0 | 4 ± 3 |
Data are given as the percentage of chimeric cells.
NKs indicate natural killer cells; DCs, dendritic cells.
Results from peripheral blood harvested 6 weeks after stem cell transplantation (C57BL/6 + SJL/J → BALB/c); n = 8. Similar experiments were repeated twice.
Results from spleen cells harvested 120 days after stem cell transplantation; n = 6.