Influence of acute GVHD on ex vivo thymic function and lymphocyte cell surface markers at 1 y after transplantation
| Parameter . | GVHD (n = 9) . | No GVHD (n = 11) . | P . |
|---|---|---|---|
| TREC (per μg CD3+ DNA) | 1231 (1722) | 6755 (3320) | .01 |
| Lymphocyte count | 1454 (1173) | 2681 (1034) | .02 |
| CD3+ | 1087 (1006) | 1234 (866) | .75 |
| CD3+4+ | 370 (357) | 606 (415) | .21 |
| CD3+8+ | 757 (670) | 749 (535) | .99 |
| CD3−16+56+ | 187 (100) | 368 (274) | .32 |
| CD3+4+28+ | 197 (99) | 576 (377) | .03 |
| CD3+4−28+ | 181 (110) | 375 (261) | .10 |
| CD3+4+DR+ | 192 (288) | 106 (91) | .94 |
| CD3+4−DR+ | 453 (517) | 275 (300) | .46 |
| CD3+4+45ROb− | 128 (175) | 407 (332) | .10 |
| CD3+4+45ROb+ | 242 (189) | 199 (101) | .88 |
| CD3+4−45ROb− | 511 (563) | 593 (425) | .51 |
| CD3+4−45ROb+ | 246 (167) | 156 (132) | .19 |
| CD19+ | 239 (252) | 753 (506) | .01 |
| CD19+5+ | 96 (64) | 292 (278) | .05 |
| CD19+27− | 218 (231) | 658 (492) | .01 |
| Parameter . | GVHD (n = 9) . | No GVHD (n = 11) . | P . |
|---|---|---|---|
| TREC (per μg CD3+ DNA) | 1231 (1722) | 6755 (3320) | .01 |
| Lymphocyte count | 1454 (1173) | 2681 (1034) | .02 |
| CD3+ | 1087 (1006) | 1234 (866) | .75 |
| CD3+4+ | 370 (357) | 606 (415) | .21 |
| CD3+8+ | 757 (670) | 749 (535) | .99 |
| CD3−16+56+ | 187 (100) | 368 (274) | .32 |
| CD3+4+28+ | 197 (99) | 576 (377) | .03 |
| CD3+4−28+ | 181 (110) | 375 (261) | .10 |
| CD3+4+DR+ | 192 (288) | 106 (91) | .94 |
| CD3+4−DR+ | 453 (517) | 275 (300) | .46 |
| CD3+4+45ROb− | 128 (175) | 407 (332) | .10 |
| CD3+4+45ROb+ | 242 (189) | 199 (101) | .88 |
| CD3+4−45ROb− | 511 (563) | 593 (425) | .51 |
| CD3+4−45ROb+ | 246 (167) | 156 (132) | .19 |
| CD19+ | 239 (252) | 753 (506) | .01 |
| CD19+5+ | 96 (64) | 292 (278) | .05 |
| CD19+27− | 218 (231) | 658 (492) | .01 |
All lymphocyte values are presented as mean (SD) of absolute number/mm3. Mann-Whitney U test.