Relative abundance of ADA alleles and ADA transcripts in lymphoid cells derived from Sib B
| Source . | Genomic DNA . | cDNA . | ||||
|---|---|---|---|---|---|---|
| Clones examined . | MutA (%) . | MutAΔ11 (%) . | Clones examined . | 13-nt insert (%) . | No insert (%) . | |
| T cells (before treatment) | 20 | 13 (65) | 7 (35) | |||
| T cells (after treatment) | 14 | 13 (93) | 1 (7) | |||
| EBV B LCL | 15 | 9 (60) | 6 (40) | |||
| T cells (after treatment) | 70 | 66 (94) | 4 (6) | |||
| Source . | Genomic DNA . | cDNA . | ||||
|---|---|---|---|---|---|---|
| Clones examined . | MutA (%) . | MutAΔ11 (%) . | Clones examined . | 13-nt insert (%) . | No insert (%) . | |
| T cells (before treatment) | 20 | 13 (65) | 7 (35) | |||
| T cells (after treatment) | 14 | 13 (93) | 1 (7) | |||
| EBV B LCL | 15 | 9 (60) | 6 (40) | |||
| T cells (after treatment) | 70 | 66 (94) | 4 (6) | |||
See “Materials and methods” for details.