Donor leucocyte infusions
Patient no. . | Indication . | DLI dose3-150 (mo after transplantation) . | Response . | GVHD . |
---|---|---|---|---|
12 | Persistent disease/ mixed chimerism | 1 (7+) 3 (14+) | > 50% response/ full donor chimerism | II |
16 | Immune reconstitution | 1 (8+) | Increase in CD4+ T-cells | 0 |
17 | Mixed chimerism | 1 (9+) | Full donor chimerism | I |
18 | Persistent disease | 1 (6+) | > 50% response | 0 |
3 (9+) | ||||
10 (12+) | ||||
20 | Progression | 10 (5+) | No response | III |
37 | Persistent disease | 1 (6+) | NE | II |
Patient no. . | Indication . | DLI dose3-150 (mo after transplantation) . | Response . | GVHD . |
---|---|---|---|---|
12 | Persistent disease/ mixed chimerism | 1 (7+) 3 (14+) | > 50% response/ full donor chimerism | II |
16 | Immune reconstitution | 1 (8+) | Increase in CD4+ T-cells | 0 |
17 | Mixed chimerism | 1 (9+) | Full donor chimerism | I |
18 | Persistent disease | 1 (6+) | > 50% response | 0 |
3 (9+) | ||||
10 (12+) | ||||
20 | Progression | 10 (5+) | No response | III |
37 | Persistent disease | 1 (6+) | NE | II |
NE indicates not evaluated.
CD3+ T-cell dose administered × 106/kg.