Clinical data of patients with adult T-cell leukemia
| Case . | Clinical type . | Age . | Sex . | WBC (/mL) . | Ly (including abnormal cells) (%) . | Surface marker . | Provirus type* . | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| CD2 . | CD3 . | CD4 . | CD8 . | CD25 . | |||||||
| 1 | Acute | 64 | M | 228 000 | 92 | ND | 80.6 | 99.4 | 3.3 | 89.2 | Defective type 2 |
| 2 | Acute | 84 | M | 16 300 | 52 | 96.4 | 94.5 | 96.5 | 1.5 | 82.1 | Complete |
| 3 | Acute | 43 | F | 14 900 | 62 | 99.0 | 97.0 | 97.2 | 5.4 | 77.9 | Multiple |
| 4 | Acute | 50 | M | 54 700 | 91 | 99.2 | 98.7 | 98.2 | 1.1 | 97.1 | Defective type 1 |
| 5 | Acute | 63 | M | 15 300 | 91 | 97.3 | 91.0 | 95.0 | 2.0 | 92.0 | Complete |
| 6 | Acute | 75 | F | 26 500 | 40 | 98.1 | 96.4 | 92.9 | 4.5 | 91.2 | ND |
| 7 | Acute | 54 | M | 75 500 | 92 | ND | ND | ND | ND | ND | Defective type 1 |
| 8 | Acute | 69 | F | 14 900 | 45 | 96.2 | 87.8 | 91.8 | 5.3 | 81.6 | Defective type 1 |
| 9 | Acute | 50 | F | 52 700 | 71 | 99.2 | 98.5 | 98.6 | 2.8 | 69.1 | Complete |
| 10 | Acute | 77 | M | 169 800 | 90 | 98.6 | 62.2 | 93.3 | 4.4 | 71.7 | Complete |
| 11 | Acute | 73 | M | 20 700 | 71 | 96.6 | 5.5 | 91.2 | 5.0 | 77.3 | Defective type 1 |
| 12 | Acute | 79 | M | 142 800 | 99 | 98.6 | 97.1 | 97.8 | 2.0 | 75.5 | Complete |
| 13 | Chronic | 44 | F | 29 800 | 67 | ND | ND | ND | ND | ND | Defective type 1 |
| 14 | Chronic | 45 | F | 86 100 | 60 | 99.4 | 98.7 | 98.3 | 7.0 | 94.2 | Complete |
| 15 | Chronic | 61 | M | 53 900 | 99 | 98.9 | 58.7 | 95.9 | 15.3 | 94.8 | Complete |
| Case . | Clinical type . | Age . | Sex . | WBC (/mL) . | Ly (including abnormal cells) (%) . | Surface marker . | Provirus type* . | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| CD2 . | CD3 . | CD4 . | CD8 . | CD25 . | |||||||
| 1 | Acute | 64 | M | 228 000 | 92 | ND | 80.6 | 99.4 | 3.3 | 89.2 | Defective type 2 |
| 2 | Acute | 84 | M | 16 300 | 52 | 96.4 | 94.5 | 96.5 | 1.5 | 82.1 | Complete |
| 3 | Acute | 43 | F | 14 900 | 62 | 99.0 | 97.0 | 97.2 | 5.4 | 77.9 | Multiple |
| 4 | Acute | 50 | M | 54 700 | 91 | 99.2 | 98.7 | 98.2 | 1.1 | 97.1 | Defective type 1 |
| 5 | Acute | 63 | M | 15 300 | 91 | 97.3 | 91.0 | 95.0 | 2.0 | 92.0 | Complete |
| 6 | Acute | 75 | F | 26 500 | 40 | 98.1 | 96.4 | 92.9 | 4.5 | 91.2 | ND |
| 7 | Acute | 54 | M | 75 500 | 92 | ND | ND | ND | ND | ND | Defective type 1 |
| 8 | Acute | 69 | F | 14 900 | 45 | 96.2 | 87.8 | 91.8 | 5.3 | 81.6 | Defective type 1 |
| 9 | Acute | 50 | F | 52 700 | 71 | 99.2 | 98.5 | 98.6 | 2.8 | 69.1 | Complete |
| 10 | Acute | 77 | M | 169 800 | 90 | 98.6 | 62.2 | 93.3 | 4.4 | 71.7 | Complete |
| 11 | Acute | 73 | M | 20 700 | 71 | 96.6 | 5.5 | 91.2 | 5.0 | 77.3 | Defective type 1 |
| 12 | Acute | 79 | M | 142 800 | 99 | 98.6 | 97.1 | 97.8 | 2.0 | 75.5 | Complete |
| 13 | Chronic | 44 | F | 29 800 | 67 | ND | ND | ND | ND | ND | Defective type 1 |
| 14 | Chronic | 45 | F | 86 100 | 60 | 99.4 | 98.7 | 98.3 | 7.0 | 94.2 | Complete |
| 15 | Chronic | 61 | M | 53 900 | 99 | 98.9 | 58.7 | 95.9 | 15.3 | 94.8 | Complete |
WBC indicates white blood cell; Ly, lymphocytes; and ND, not determined.
Provirus type of human T-cell leukemia virus type I is determined by Southern blot and polymerase chain reaction as described previously.32