Table 1.

Patient and disease characteristics

45  
Median age, y (range) 49  (20-68)  
Sex, male/female 28/17 
Median no. of prior therapies (range) 2 (0-5)  
Median follow-up, d (range) 372  (24-820)  
Prior ABMT 26  
CMV status neg/neg 0  
Thiotepa mg/kg, 15/10/5 14/24/7 
Stem cell source  
 marrow 17  
 PBPC 28  
Median CD 34+ × 10e6/kg, BM/PBPC 3.8/5.7  
Donor type  
 6 of 6 matched related 42  
 5 of 6 mismatched related 3  
Diagnosis and status at transplantation  
 AML/RAEB-t/ALL 5/6/1 
 CR1 3  
 ≥CR2 2  
 Untreated 
 Refractory 3  
Indolent/high-grade lymphoma 13/11  
 CR1 1  
 PR 
 ≥CR2 4  
 Refractory 9  
Hodgkin disease/multiple myeloma 4/5  
 CR1 0  
 PR 2  
 ≥CR2 
 Untreated relapse 1  
 Refractory 
45  
Median age, y (range) 49  (20-68)  
Sex, male/female 28/17 
Median no. of prior therapies (range) 2 (0-5)  
Median follow-up, d (range) 372  (24-820)  
Prior ABMT 26  
CMV status neg/neg 0  
Thiotepa mg/kg, 15/10/5 14/24/7 
Stem cell source  
 marrow 17  
 PBPC 28  
Median CD 34+ × 10e6/kg, BM/PBPC 3.8/5.7  
Donor type  
 6 of 6 matched related 42  
 5 of 6 mismatched related 3  
Diagnosis and status at transplantation  
 AML/RAEB-t/ALL 5/6/1 
 CR1 3  
 ≥CR2 2  
 Untreated 
 Refractory 3  
Indolent/high-grade lymphoma 13/11  
 CR1 1  
 PR 
 ≥CR2 4  
 Refractory 9  
Hodgkin disease/multiple myeloma 4/5  
 CR1 0  
 PR 2  
 ≥CR2 
 Untreated relapse 1  
 Refractory 

ABMT indicates autologous bone marrow transplantation; CMV, cytomegalovirus; PBPC, mobilized peripheral blood cells; BM, marrow cells; AML, acute myelogenous leukemia; RAEB-t, refractory anemia with excess of blasts in transformation; ALL, acute lymphocytic leukemia; CR, complete remission; and PR, partial remission.

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