Table 1. Main features of KG1a, HL60,... | American Society of Hematology

Table 1.

Main features of KG1a, HL60, NB4, and THP-1 cell lines

	KG1a	HL60	NB4	THP-1
Origin	AML-M0	AML-M2	AML-M3	AML-M5
Cytologic features	Myeloblasts	Myeloblasts	Promyelocytes	Monoblasts
Immunophenotype	CD34⁺⁺⁺CD38⁻	CD34⁺⁺⁺CD38⁻	CD34⁺⁺⁺CD38⁻	CD34⁺⁺⁺CD38⁻
	CD11b⁻CD14⁻CD15^low/−	CD11b⁻CD14⁻CD15^low	CD11b⁻CD14⁻CD15^low	CD11b⁻CD14⁻CD15^low

	KG1a	HL60	NB4	THP-1
Origin	AML-M0	AML-M2	AML-M3	AML-M5
Cytologic features	Myeloblasts	Myeloblasts	Promyelocytes	Monoblasts
Immunophenotype	CD34⁺⁺⁺CD38⁻	CD34⁺⁺⁺CD38⁻	CD34⁺⁺⁺CD38⁻	CD34⁺⁺⁺CD38⁻
	CD11b⁻CD14⁻CD15^low/−	CD11b⁻CD14⁻CD15^low	CD11b⁻CD14⁻CD15^low	CD11b⁻CD14⁻CD15^low

KG1a, HL60, NB4, and THP-1 cells are human AML cell lines blocked at distinct stages of granulomonocytic differentiation. They are characterized by specific cytologic and antigenic features closely similar to those displayed by AML blasts from distinct subtypes, as indicated.

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