Table 2. Patients with a diagnosis of... | American Society of Hematology

Table 2.

Patients with a diagnosis of EBV-associated HLH

Patient	Age/sex	NK LU	% NK	% perforin
Patient	Age/sex	NK LU	% NK	NK	CD8	CD56
P8	1 y/M	4.3	<1↓	88	81↑	32
P5	2 y/M	NA	1↓	96	26↑	24
P4	4 y/M	0.02↓	<1↓	82	9	28
P3	11 y/M	0.00↓	3↓	85	66↑	76↑
Normal values	1-15 y	>3.2	4-22	81-91	2-11	12-34

Patient	Age/sex	NK LU	% NK	% perforin
Patient	Age/sex	NK LU	% NK	NK	CD8	CD56
P8	1 y/M	4.3	<1↓	88	81↑	32
P5	2 y/M	NA	1↓	96	26↑	24
P4	4 y/M	0.02↓	<1↓	82	9	28
P3	11 y/M	0.00↓	3↓	85	66↑	76↑
Normal values	1-15 y	>3.2	4-22	81-91	2-11	12-34

Patients with EBV-associated HLH were generally older at diagnosis and were more likely to have very low numbers of NK cells and increased perforin-expressing CD8⁺ T cells. Perforin-expressing CD8⁺ T cells of patient P4 did not show an increased value, but the specimen of this patient was drawn a couple of weeks after initiation of therapy.

NA indicates not applicable.

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