Number of CFU-Sd12 colonies before and after HOXA10 induction
| Mouse line . | Number of spleen colonies/104 input cells with doxycycline . | Number of spleen colonies/104 input cells without doxycycline . |
|---|---|---|
| HOXA10 2-5 | 7.8 ± 0.8 (n = 6) | 7.2 ± 1.5 (n = 6) |
| HOXA10 17-3 | 7.4 ± 1.5 (n = 5) | 7.0 ± 0.7 (n = 5) |
| Control mice | Not done | 7.2 ± 1.6 (n = 5) |
| Mouse line . | Number of spleen colonies/104 input cells with doxycycline . | Number of spleen colonies/104 input cells without doxycycline . |
|---|---|---|
| HOXA10 2-5 | 7.8 ± 0.8 (n = 6) | 7.2 ± 1.5 (n = 6) |
| HOXA10 17-3 | 7.4 ± 1.5 (n = 5) | 7.0 ± 0.7 (n = 5) |
| Control mice | Not done | 7.2 ± 1.6 (n = 5) |
Number of day 12 CFU-S macroscopic spleen colonies derived from 104 input BM cells that were transduced with NIT-GFP and injected immediately after the viral coculture. Doxycycline was added to the drinking water (0.2 mg/mL in 3% sucrose) of the corresponding recipient mice. Results are expressed as means ± SD from 2 independent experiments. Numbers in parentheses indicate the number of spleens analyzed.