Allelic frequencies of the more common A, B, DR, DQ, and Cw alleles in patients and controls
| . | HLA-A . | . | HLA-B . | . | HLA-C . | . | HLA-DR . | . | HLA-DQ . | |||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| C . | AA . | MDS . | PNH . | C . | AA . | MDS . | PNH . | C . | AA . | MDS . | PNH . | C . | AA . | MDS . | PNH . | C . | AA . | MDS . | PNH . | |||||
| A1 | 24 | 18 | 29 | 25 | B5 | 13 | 11 | 15 | 14 | Cw1 | 09 | 07 | 11 | 06 | DR1 | 18 | 17 | 18 | 09 | DQ1 | 68 | 59 | 66 | 72 |
| A2 | 47 | 47 | 46 | 45 | B7 | 21 | 23 | 25 | 31 | Cw2 | 10 | 10 | 08 | 13 | DR2 | 28 | 43 | 40 | 58 | DQ2 | 40 | 28 | 31 | 28 |
| A3 | 22 | 23 | 24 | 23 | B8 | 15 | 16 | 16 | 16 | Cw3 | 23 | 19 | 25 | 13 | DR3 | 20 | 21 | 19 | 21 | DQ3 | 48 | 47 | 50 | 55 |
| A9 | 23 | 20 | 21 | 20 | B12 | 25 | 21 | 25 | 14 | Cw4 | 26 | 23 | 18 | 24 | DR4 | 29 | 25 | 29 | 33 | DQ4 | 06 | 03 | 04 | 05 |
| A10 | 12 | 15 | 17 | 12 | B13 | 04 | 05 | 03 | 04 | Cw5 | 10 | 06 | 14 | 08 | DR5 | 24 | 28 | 22 | 28 | |||||
| A11 | 12 | 12 | 13 | 15 | B14 | 08 | 15 | 09 | 08 | Cw6 | 12 | 16 | 23 | 16 | DR6 | 28 | 23 | 20 | 17 | |||||
| A19 | 29 | 34 | 27 | 25 | B15 | 12 | 10 | 15 | 10 | Cw7 | 45 | 49 | 44 | 57 | DR7 | 23 | 17 | 22 | 10 | |||||
| A28 | 10 | 12 | 10 | 12 | B16 | 09 | 06 | 07 | 09 | Cw8 | 11 | 13 | 09 | 09 | DR8 | 08 | 08 | 06 | 08 | |||||
| B17 | 10 | 08 | 10 | 08 | Cw12 | 06 | 03 | 11 | 10 | DR9 | 03 | 03 | 03 | 01 | ||||||||||
| B18 | 09 | 08 | 08 | 11 | Cw15 | 07 | 05 | 02 | 05 | DR10 | 03 | 01 | 03 | 01 | ||||||||||
| B21 | 06 | 07 | 06 | 01 | Cw16 | 08 | 03 | 02 | 06 | |||||||||||||||
| B22 | 04 | 05 | 02 | 05 | ||||||||||||||||||||
| B27 | 07 | 07 | 10 | 05 | ||||||||||||||||||||
| B35 | 19 | 16 | 15 | 18 | ||||||||||||||||||||
| B37 | 02 | 02 | 06 | 03 | ||||||||||||||||||||
| B40 | 13 | 16 | 10 | 16 | ||||||||||||||||||||
| . | HLA-A . | . | HLA-B . | . | HLA-C . | . | HLA-DR . | . | HLA-DQ . | |||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| C . | AA . | MDS . | PNH . | C . | AA . | MDS . | PNH . | C . | AA . | MDS . | PNH . | C . | AA . | MDS . | PNH . | C . | AA . | MDS . | PNH . | |||||
| A1 | 24 | 18 | 29 | 25 | B5 | 13 | 11 | 15 | 14 | Cw1 | 09 | 07 | 11 | 06 | DR1 | 18 | 17 | 18 | 09 | DQ1 | 68 | 59 | 66 | 72 |
| A2 | 47 | 47 | 46 | 45 | B7 | 21 | 23 | 25 | 31 | Cw2 | 10 | 10 | 08 | 13 | DR2 | 28 | 43 | 40 | 58 | DQ2 | 40 | 28 | 31 | 28 |
| A3 | 22 | 23 | 24 | 23 | B8 | 15 | 16 | 16 | 16 | Cw3 | 23 | 19 | 25 | 13 | DR3 | 20 | 21 | 19 | 21 | DQ3 | 48 | 47 | 50 | 55 |
| A9 | 23 | 20 | 21 | 20 | B12 | 25 | 21 | 25 | 14 | Cw4 | 26 | 23 | 18 | 24 | DR4 | 29 | 25 | 29 | 33 | DQ4 | 06 | 03 | 04 | 05 |
| A10 | 12 | 15 | 17 | 12 | B13 | 04 | 05 | 03 | 04 | Cw5 | 10 | 06 | 14 | 08 | DR5 | 24 | 28 | 22 | 28 | |||||
| A11 | 12 | 12 | 13 | 15 | B14 | 08 | 15 | 09 | 08 | Cw6 | 12 | 16 | 23 | 16 | DR6 | 28 | 23 | 20 | 17 | |||||
| A19 | 29 | 34 | 27 | 25 | B15 | 12 | 10 | 15 | 10 | Cw7 | 45 | 49 | 44 | 57 | DR7 | 23 | 17 | 22 | 10 | |||||
| A28 | 10 | 12 | 10 | 12 | B16 | 09 | 06 | 07 | 09 | Cw8 | 11 | 13 | 09 | 09 | DR8 | 08 | 08 | 06 | 08 | |||||
| B17 | 10 | 08 | 10 | 08 | Cw12 | 06 | 03 | 11 | 10 | DR9 | 03 | 03 | 03 | 01 | ||||||||||
| B18 | 09 | 08 | 08 | 11 | Cw15 | 07 | 05 | 02 | 05 | DR10 | 03 | 01 | 03 | 01 | ||||||||||
| B21 | 06 | 07 | 06 | 01 | Cw16 | 08 | 03 | 02 | 06 | |||||||||||||||
| B22 | 04 | 05 | 02 | 05 | ||||||||||||||||||||
| B27 | 07 | 07 | 10 | 05 | ||||||||||||||||||||
| B35 | 19 | 16 | 15 | 18 | ||||||||||||||||||||
| B37 | 02 | 02 | 06 | 03 | ||||||||||||||||||||
| B40 | 13 | 16 | 10 | 16 | ||||||||||||||||||||
HLA allelic frequencies found within all patients with AA, MDS, and all those with PNH clone (in percent) in comparison to controls (C). For comparison to control groups, molecular typings were converted into serologic nomenclature (parent antigens).