Glycophorin C genotype and infections over time
| . | . | wt/wt* . | wt/Δ† . | Δ/Δ‡ . | P . | ||||
|---|---|---|---|---|---|---|---|---|---|
| Month . | No.1-153 . | Prevalence (%) . | Parasitemia1-155 (95% CI) . | Prevalence (%) . | Parasitemia (95% CI) . | Prevalence (%) . | Parasitemia (95% CI) . | Prevalence1-154 . | Parasitemia1-159 . |
| Glycophorin C genotype and P falciparum | |||||||||
| July | 696 | 34/200 (17.0)1-160 | 2.21 (2.16-2.62) | 72/345 (20.9) | 2.42 (2.28-2.55) | 34/151 (22.5) | 2.38 (2.24-2.71) | .392 | .880 |
| Aug | 528 | 27/139 (19.4)1-160 | 2.30 (2.27-2.70) | 60/264 (22.7) | 2.38 (2.24-2.54) | 30/125 (24.0) | 2.38 (2.21-2.72) | .638 | .739 |
| Sept | 415 | 23/121 (19.0)1-160 | 2.30 (2.16-2.57) | 56/199 (28.1) | 2.15 (2.14-2.49) | 19/95 (20.0) | 2.08 (2.02-2.47) | .112 | .627 |
| Oct | 466 | 23/136 (16.9)1-160 | 2.21 (2.06-2.56) | 41/235 (17.5) | 2.30 (2.29-2.70) | 24/95 (25.3) | 2.08 (2.04-2.76) | .203 | .315 |
| Nov | 495 | 35/130 (26.9)1-160 | 2.68 (2.44-3.00) | 75/248 (30.2) | 2.30 (2.31-2.64) | 36/117 (30.8) | 2.34 (2.21-2.72) | .752 | .211 |
| Dec | 331 | 25/85 (29.4)1-160 | 2.45 (2.29-3.03) | 43/171 (25.2) | 2.56 (2.47-2.97) | 18/75 (24.0) | 2.85 (2.46-3.25) | .692 | .586 |
| Jan | 325 | 25/93 (26.9)1-160 | 3.00 (2.73-3.28) | 37/162 (22.8) | 2.60 (2.67-3.23) | 17/70 (24.3) | 2.38 (2.12-2.92) | .769 | .049 |
| Glycophorin C genotype and P vivax | |||||||||
| July | 696 | 35/200 (17.5)1-164 | 1.91 (1.95-2.32) | 63/345 (18.3) | 2.21 (2.20-2.48) | 26/151 (17.2) | 2.38 (2.27-2.78) | .953 | .026 |
| Aug | 528 | 30/139 (21.6)1-164 | 2.08 (1.95-2.31) | 52/264 (19.7) | 1.91 (1.98-2.25) | 29/125 (23.2) | 2.08 (1.96-2.28) | .663 | .952 |
| Sep | 415 | 21/121 (17.4)1-164 | 2.08 (1.93-2.22) | 38/199 (19.1) | 1.91 (1.96-2.28) | 20/95 (21.1) | 2.15 (2.00-2.44) | .789 | .479 |
| Oct | 466 | 35/136 (25.7)1-164 | 2.08 (2.02-2.30) | 52/235 (22.1) | 2.08 (2.05-2.25) | 26/95 (27.4) | 2.30 (2.13-2.62) | .537 | .230 |
| Nov | 495 | 23/130 (17.7)1-164 | 2.08 (2.03-2.64) | 41/248 (16.5) | 2.08 (2.06-2.39) | 19/117 (16.2) | 1.91 (1.87-2.43) | .945 | .594 |
| Dec | 331 | 5/85 (5.9)1-164 | 1.91 (1.40-2.49) | 21/171 (12.3) | 2.21 (1.98-2.52) | 8/75 (10.7) | 2.26 (1.87-2.67) | .281 | .382 |
| Jan | 325 | 8/93 (8.6)1-164 | 2.60 (2.04-2.81) | 14/162 (8.6) | 2.21 (2.00-2.71) | 1/70 (1.4) | 1.61 (N/A) | .115 | .298 |
| . | . | wt/wt* . | wt/Δ† . | Δ/Δ‡ . | P . | ||||
|---|---|---|---|---|---|---|---|---|---|
| Month . | No.1-153 . | Prevalence (%) . | Parasitemia1-155 (95% CI) . | Prevalence (%) . | Parasitemia (95% CI) . | Prevalence (%) . | Parasitemia (95% CI) . | Prevalence1-154 . | Parasitemia1-159 . |
| Glycophorin C genotype and P falciparum | |||||||||
| July | 696 | 34/200 (17.0)1-160 | 2.21 (2.16-2.62) | 72/345 (20.9) | 2.42 (2.28-2.55) | 34/151 (22.5) | 2.38 (2.24-2.71) | .392 | .880 |
| Aug | 528 | 27/139 (19.4)1-160 | 2.30 (2.27-2.70) | 60/264 (22.7) | 2.38 (2.24-2.54) | 30/125 (24.0) | 2.38 (2.21-2.72) | .638 | .739 |
| Sept | 415 | 23/121 (19.0)1-160 | 2.30 (2.16-2.57) | 56/199 (28.1) | 2.15 (2.14-2.49) | 19/95 (20.0) | 2.08 (2.02-2.47) | .112 | .627 |
| Oct | 466 | 23/136 (16.9)1-160 | 2.21 (2.06-2.56) | 41/235 (17.5) | 2.30 (2.29-2.70) | 24/95 (25.3) | 2.08 (2.04-2.76) | .203 | .315 |
| Nov | 495 | 35/130 (26.9)1-160 | 2.68 (2.44-3.00) | 75/248 (30.2) | 2.30 (2.31-2.64) | 36/117 (30.8) | 2.34 (2.21-2.72) | .752 | .211 |
| Dec | 331 | 25/85 (29.4)1-160 | 2.45 (2.29-3.03) | 43/171 (25.2) | 2.56 (2.47-2.97) | 18/75 (24.0) | 2.85 (2.46-3.25) | .692 | .586 |
| Jan | 325 | 25/93 (26.9)1-160 | 3.00 (2.73-3.28) | 37/162 (22.8) | 2.60 (2.67-3.23) | 17/70 (24.3) | 2.38 (2.12-2.92) | .769 | .049 |
| Glycophorin C genotype and P vivax | |||||||||
| July | 696 | 35/200 (17.5)1-164 | 1.91 (1.95-2.32) | 63/345 (18.3) | 2.21 (2.20-2.48) | 26/151 (17.2) | 2.38 (2.27-2.78) | .953 | .026 |
| Aug | 528 | 30/139 (21.6)1-164 | 2.08 (1.95-2.31) | 52/264 (19.7) | 1.91 (1.98-2.25) | 29/125 (23.2) | 2.08 (1.96-2.28) | .663 | .952 |
| Sep | 415 | 21/121 (17.4)1-164 | 2.08 (1.93-2.22) | 38/199 (19.1) | 1.91 (1.96-2.28) | 20/95 (21.1) | 2.15 (2.00-2.44) | .789 | .479 |
| Oct | 466 | 35/136 (25.7)1-164 | 2.08 (2.02-2.30) | 52/235 (22.1) | 2.08 (2.05-2.25) | 26/95 (27.4) | 2.30 (2.13-2.62) | .537 | .230 |
| Nov | 495 | 23/130 (17.7)1-164 | 2.08 (2.03-2.64) | 41/248 (16.5) | 2.08 (2.06-2.39) | 19/117 (16.2) | 1.91 (1.87-2.43) | .945 | .594 |
| Dec | 331 | 5/85 (5.9)1-164 | 1.91 (1.40-2.49) | 21/171 (12.3) | 2.21 (1.98-2.52) | 8/75 (10.7) | 2.26 (1.87-2.67) | .281 | .382 |
| Jan | 325 | 8/93 (8.6)1-164 | 2.60 (2.04-2.81) | 14/162 (8.6) | 2.21 (2.00-2.71) | 1/70 (1.4) | 1.61 (N/A) | .115 | .298 |
CI indicates confidence interval.
Homozygous wild type individuals.
Heterozygotes for glycophorin C exon 3 deletion.
Homozygotes for glycophorin C exon 3 deletion.
Total number of individuals examined each month.
Median parasite density in log10parasites/μL.
χ2 test.
Kruskal-Wallis test.
Number of individuals with P falciparum detected on blood smear.
Number of individuals with P vivax detected on blood smear.