Table 1.

Exclusions from the total sample of Caucasian and African Americans at least 20 y of age

ExclusionAfrican AmericanCaucasian
MenWomenMenWomen
Total sample 4121 4635 4921 5586  
Excluded for     
 Age younger than 20 y 2002 2045 1634 1752  
 Pregnant 90 70 
 Transferrin saturation not measured 183 208 119 180 
 Abnormal hemoglobin level* 230 610 347 272 
 Abnormal hematocrit 52 48 68 
 Protoporphyrin greater than or equal to 70 μg/dL red blood cells 41 148 121 358  
 MCV less than 80 fL 127 96 50 55  
 Serum alanine aminotransferase greater than 80 15 15 11 20  
 Serum aspartate aminotransferase greater than 74 U/L 18 4  
 Serum γ-glutamyl transferase greater than 102 71 82 64 90 
 Serum total bilirubin greater than 2.0 mg/dL 23 
 Serum lactate dehydrogenase greater than 546 
 Serum C-reactive protein greater than 1.0 mg/dL 69 163 124 207  
 Serum hepatitis B surface antigen positive or borderline 17 4  
 Serum hepatitis C antibody positive 41 20 39 18 
Subtotal 1301 1089 2328 2483  
 Possible heterozygosity for hemochromatosis (non-Hispanic blacks only) 43 36 0  
Sample for transferrin saturation modeling 1258 1053 2328 2483  
 Serum ferritin not measured 8  
Sample for serum ferritin analysis 1252 1047 2322 2475 
ExclusionAfrican AmericanCaucasian
MenWomenMenWomen
Total sample 4121 4635 4921 5586  
Excluded for     
 Age younger than 20 y 2002 2045 1634 1752  
 Pregnant 90 70 
 Transferrin saturation not measured 183 208 119 180 
 Abnormal hemoglobin level* 230 610 347 272 
 Abnormal hematocrit 52 48 68 
 Protoporphyrin greater than or equal to 70 μg/dL red blood cells 41 148 121 358  
 MCV less than 80 fL 127 96 50 55  
 Serum alanine aminotransferase greater than 80 15 15 11 20  
 Serum aspartate aminotransferase greater than 74 U/L 18 4  
 Serum γ-glutamyl transferase greater than 102 71 82 64 90 
 Serum total bilirubin greater than 2.0 mg/dL 23 
 Serum lactate dehydrogenase greater than 546 
 Serum C-reactive protein greater than 1.0 mg/dL 69 163 124 207  
 Serum hepatitis B surface antigen positive or borderline 17 4  
 Serum hepatitis C antibody positive 41 20 39 18 
Subtotal 1301 1089 2328 2483  
 Possible heterozygosity for hemochromatosis (non-Hispanic blacks only) 43 36 0  
Sample for transferrin saturation modeling 1258 1053 2328 2483  
 Serum ferritin not measured 8  
Sample for serum ferritin analysis 1252 1047 2322 2475 
*

Hemoglobin (Hb) level exclusions: African American men, Hb less than 13 g/dL; African American women, Hb less than 11.5 g/dL; Caucasian men, Hb less than 13.5 g/dL; Caucasian women, Hb less than 12 g/dL.

Hematocrit (Hct) exclusions: African American men, Hct less than 34%; African American women, Hct less than 30%; Caucasian men, Hct less than 40%; Caucasian women, Hct less than 36%.

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