Clinical outcome in FLT3/ITD− and FLT3/ITD+ patients
| . | Total . | FLT3/ITD− . | FLT3/ITD+ . | P . |
|---|---|---|---|---|
| No. of patients | 854 | 627 | 227 | |
| CR | 82% | 84% | 78% | .05 |
| ID | 8% | 7% | 11% | .04 |
| RD | 10% | 9% | 11% | .4 |
| Outcome at 5 y | ||||
| RR | 49% (2.1) | 44% (2.4) | 64% (4.1) | < .001 |
| DFS | 42% (2.0) | 46% (2.3) | 30% (3.6) | < .001 |
| EFS | 35% (1.7) | 39% (2.0) | 23% (2.9) | < .001 |
| OS | 41% (1.8) | 44% (2.1) | 32% (3.2) | < .001 |
| . | Total . | FLT3/ITD− . | FLT3/ITD+ . | P . |
|---|---|---|---|---|
| No. of patients | 854 | 627 | 227 | |
| CR | 82% | 84% | 78% | .05 |
| ID | 8% | 7% | 11% | .04 |
| RD | 10% | 9% | 11% | .4 |
| Outcome at 5 y | ||||
| RR | 49% (2.1) | 44% (2.4) | 64% (4.1) | < .001 |
| DFS | 42% (2.0) | 46% (2.3) | 30% (3.6) | < .001 |
| EFS | 35% (1.7) | 39% (2.0) | 23% (2.9) | < .001 |
| OS | 41% (1.8) | 44% (2.1) | 32% (3.2) | < .001 |
P values are for Mantel-Haenszel test for trend for CR and reasons for failure, and log-rank test for outcome at 5 years. Figures in parentheses are SEs.