Hematologic side effects with PEG IFN-α-2b
| Dose level (μg/kg/wk) . | No. . | Anemia . | Thrombocytopenia . | Granulocytopenia . | |||
|---|---|---|---|---|---|---|---|
| 2 . | 3-4 . | 2 . | 3-4 . | 2 . | 3-4 . | ||
| 0.75 | 3 | ||||||
| 1.5 | 3 | 1 | 1 | ||||
| 3 | 3 | 1 | |||||
| 4.5 | 3 | 1 | |||||
| 6 | 3 | 1 | |||||
| 7.5 | 6 | 1 | 1 | 1 | 2 | 1 | 1 |
| 9 | 6 | 1 | 3 | 2 | 2 | ||
| Dose level (μg/kg/wk) . | No. . | Anemia . | Thrombocytopenia . | Granulocytopenia . | |||
|---|---|---|---|---|---|---|---|
| 2 . | 3-4 . | 2 . | 3-4 . | 2 . | 3-4 . | ||
| 0.75 | 3 | ||||||
| 1.5 | 3 | 1 | 1 | ||||
| 3 | 3 | 1 | |||||
| 4.5 | 3 | 1 | |||||
| 6 | 3 | 1 | |||||
| 7.5 | 6 | 1 | 1 | 1 | 2 | 1 | 1 |
| 9 | 6 | 1 | 3 | 2 | 2 | ||
Number of patients with toxicity grade is shown under each toxicity column.