Table 2. Characterization of additional... | American Society of Hematology

Table 2.

Characterization of additional cytogenetic changes associated with primary chromosomal aberrations in Medical Research Council trial AML11

	Cytogenetic aberration
	Total	t(15;17)	t(8;21)	inv(16)	+8	7q−	+21	9q−	+22	11q23	Other structural	Other numerical	−7	5q−	−5	abn(3q)	Complex
Total	1065	43	23	12	109	48	26	24	15	11	295	277	87	80	55	27	146
Alone		23	6	7	41	5	5	9	1	4	70	51	13	6	1	2	—
With the following:
t(15;17)	43	—	0	0	5	1	0	2	0	0	11	3^*	0	0	0	0	0^*
t(8;21)	23		—	0	1	1	0	2	0	1	0^†	13^*	1	0	0	0	0
inv(16)	12			—	1	2	0	0	1	0	2	3	0	0	0	1	1
+8	109				—	7	10^†	4	8^†	1	42^*	48^†	11	16^*	8	6	33^†
7q−	48					—	2	2	1	0	35^†	33^†	3	11^†	8^*	4	30^†
+21	26						—	1	5^†	0	16^†	17^†	2	3	3	1	13^†
9q−	24							—	0	0	8	9	3	2	1	2	6
+22	15								—	0	11^†	11^†	0	4	3	1	10^†
11q23	11									—	6	5	2	0	2	0	3
Other structural	295										—	156^†	57^†	62^†	47^†	19^†	129^†
Other numerical	277											—	53^†	56^†	50^†	15^*	140^†
−7	87												—	22^†	27^†	12^†	50^†
5q−	80													—	2	10^†	50^†
−5	55														—	3	50^†
abn(3q)	27															—	15^†
Complex	146																—

	Cytogenetic aberration
	Total	t(15;17)	t(8;21)	inv(16)	+8	7q−	+21	9q−	+22	11q23	Other structural	Other numerical	−7	5q−	−5	abn(3q)	Complex
Total	1065	43	23	12	109	48	26	24	15	11	295	277	87	80	55	27	146
Alone		23	6	7	41	5	5	9	1	4	70	51	13	6	1	2	—
With the following:
t(15;17)	43	—	0	0	5	1	0	2	0	0	11	3^*	0	0	0	0	0^*
t(8;21)	23		—	0	1	1	0	2	0	1	0^†	13^*	1	0	0	0	0
inv(16)	12			—	1	2	0	0	1	0	2	3	0	0	0	1	1
+8	109				—	7	10^†	4	8^†	1	42^*	48^†	11	16^*	8	6	33^†
7q−	48					—	2	2	1	0	35^†	33^†	3	11^†	8^*	4	30^†
+21	26						—	1	5^†	0	16^†	17^†	2	3	3	1	13^†
9q−	24							—	0	0	8	9	3	2	1	2	6
+22	15								—	0	11^†	11^†	0	4	3	1	10^†
11q23	11									—	6	5	2	0	2	0	3
Other structural	295										—	156^†	57^†	62^†	47^†	19^†	129^†
Other numerical	277											—	53^†	56^†	50^†	15^*	140^†
−7	87												—	22^†	27^†	12^†	50^†
5q−	80													—	2	10^†	50^†
−5	55														—	3	50^†
abn(3q)	27															—	15^†
Complex	146																—

P values are for Fisher exact test comparing abnormality A vs not-abnormality A with abnormality B vs not-abnormality B.

abn indicates abnormal.

P < .01.

P < .001.