Table 3.

Platelet apheresis yield by treatment group

Placebo (n = 65)PEG-rHuMGDF 1 μg/kg (n = 23)PEG-rHuMGDF 3 μg/kg (n = 22)P
Preapheresis platelet count, × 109/L3-150     
 Median 231 330 544 < .001 
 Range 155-346 208-533 341-789  
Postapheresis platelet count, × 109/L3-150     
 Median 168 247 405 < .001 
 Range 121-266 163-347 278-542  
Platelet yield, × 1011     
 Median 3.8 5.6 11.0 < .001 
 Range 1.3-7.9 2.6-12.5 7.1-18.3  
Collection efficiency3-151     
 Median 0.44 0.49 0.53 < .001 
 Range 0.18-0.72 0.13-0.58 0.45-0.64  
Placebo (n = 65)PEG-rHuMGDF 1 μg/kg (n = 23)PEG-rHuMGDF 3 μg/kg (n = 22)P
Preapheresis platelet count, × 109/L3-150     
 Median 231 330 544 < .001 
 Range 155-346 208-533 341-789  
Postapheresis platelet count, × 109/L3-150     
 Median 168 247 405 < .001 
 Range 121-266 163-347 278-542  
Platelet yield, × 1011     
 Median 3.8 5.6 11.0 < .001 
 Range 1.3-7.9 2.6-12.5 7.1-18.3  
Collection efficiency3-151     
 Median 0.44 0.49 0.53 < .001 
 Range 0.18-0.72 0.13-0.58 0.45-0.64  
F3-150

On day 15.

F3-151

Number of platelets collected/[([preapheresis count + postapheresis count]/2) × blood volume processed].

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