Lists of genes involved in cell signaling pathways
| Subgroup . | No. of genes . |
|---|---|
| Adapter proteins | 19 |
| Caspases/caspase substrates | 12 |
| Cell-cycle proteins | 95 |
| Cell surface markers | 88 |
| Clusters of differentiation | 44 |
| Coactivators/HATs | 13 |
| Corepressors | 8 |
| Cytokines/cytokine receptors | 65 |
| Cytoskeletal proteins | 61 |
| Death domain adapters | 10 |
| DNA damage repair proteins | 32 |
| Enhancer binding proteins | 69 |
| Extracellular matrix proteins | 45 |
| Glutamate receptors | 4 |
| G-protein regulators | 17 |
| G-proteins | 33 |
| Growth factors/growth factor receptors | 98 |
| Histones | 15 |
| Ion channels | 49 |
| Kinases (Pl3, Ser-Thr) | 22 |
| MAPKs/SAPsK/JAKs | 64 |
| Mitochondrial proteins | 33 |
| NOSs | 2 |
| Nuclear receptors | 24 |
| PDZ adapters | 7 |
| Phosphatases | 56 |
| Signaling effectors | 65 |
| SMADs/STATs | 10 |
| Synaptic vesicles | 17 |
| TGF/TNF | 31 |
| Transcription factors | 23 |
| Tyrosine kinases | 18 |
| Subgroup . | No. of genes . |
|---|---|
| Adapter proteins | 19 |
| Caspases/caspase substrates | 12 |
| Cell-cycle proteins | 95 |
| Cell surface markers | 88 |
| Clusters of differentiation | 44 |
| Coactivators/HATs | 13 |
| Corepressors | 8 |
| Cytokines/cytokine receptors | 65 |
| Cytoskeletal proteins | 61 |
| Death domain adapters | 10 |
| DNA damage repair proteins | 32 |
| Enhancer binding proteins | 69 |
| Extracellular matrix proteins | 45 |
| Glutamate receptors | 4 |
| G-protein regulators | 17 |
| G-proteins | 33 |
| Growth factors/growth factor receptors | 98 |
| Histones | 15 |
| Ion channels | 49 |
| Kinases (Pl3, Ser-Thr) | 22 |
| MAPKs/SAPsK/JAKs | 64 |
| Mitochondrial proteins | 33 |
| NOSs | 2 |
| Nuclear receptors | 24 |
| PDZ adapters | 7 |
| Phosphatases | 56 |
| Signaling effectors | 65 |
| SMADs/STATs | 10 |
| Synaptic vesicles | 17 |
| TGF/TNF | 31 |
| Transcription factors | 23 |
| Tyrosine kinases | 18 |
By screening the public available gene databases (http://www4.ncbi.nlm.nih.gov/ and http://www4.ncbi.nlm.nih.gov/omim/), 1149 genes that may be involved in the regulation of cellular growth and cell signaling were selected and categorized. For each of the subgroups, a separate Excel file was created containing the name of the gene, the GenBank accession number and additional information.