Table 2. Frequency of... | American Society of Hematology

Table 2.

Frequency of leukemia-associated aberrations of chromosomes 7 and 8 in the side population and non–side population stem cell compartments at initial diagnosis

Patient^*	% Blasts in BM	CD34^low/−SP	CD34⁺ non-SP
	Monosomy 7
1	< 5	6	5
2	< 5	12.5	0
3	< 5	7.4	16
4	18	68	79
5	12	12	4.5
6	15	9	18.1
7a	< 5^*	5.5	6.7
8	90	84.5	93
9	80 (PB)	90	89
	Trisomy 8
10	50	18	11.5
11	57	40	40
12	52	57.5	42.5
13	71	42.1	13.2
14	85	—	47.1
15	16	28.5	10
7b	< 5^*	11	19.5
16	< 5	2	0.5

Patient^*	% Blasts in BM	CD34^low/−SP	CD34⁺ non-SP
	Monosomy 7
1	< 5	6	5
2	< 5	12.5	0
3	< 5	7.4	16
4	18	68	79
5	12	12	4.5
6	15	9	18.1
7a	< 5^*	5.5	6.7
8	90	84.5	93
9	80 (PB)	90	89
	Trisomy 8
10	50	18	11.5
11	57	40	40
12	52	57.5	42.5
13	71	42.1	13.2
14	85	—	47.1
15	16	28.5	10
7b	< 5^*	11	19.5
16	< 5	2	0.5

The results of interphase fluorescence in situ hybridization are given as percentages of 200 sorted bone marrow cells.

BM indicates bone marrow; SP, side population; PB, peripheral blood.

Nine patients had fewer than 200 analyzable nuclei as follows: patient 1 non-SP (187 cells), patient 2 non-SP (12 cells), patient 3 SP (68 cells), patient 11 SP (30 cells), patient 12 SP (40 cells), patient 13 SP (138 cells)/non-SP (113 cells); patient 14 SP (136 cells); patient 7b SP (110 cells)/non-SP (173 cells) patient 15 non-SP (179 cells).

†

At initial diagnosis, the acute myeloid leukemia in case 7 was characterized by monosomy 7 and trisomy 8.

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