Comparison of the proportions of CD3+CD4lo T cells in the peripheral blood of young and elderly people
| . | Young . | Middle-aged . | Elderly . | P* . |
|---|---|---|---|---|
| CD4lo in CD4+, %† | 15.0 ± 4.8 | 13.8 ± 6.8 | 29.2 ± 3.1 | < .00003 |
| CD4loin PBLs, % | 5.7 ± 2.1 | 8.2 ± 1.9 | 13.6 ± 2.8 | < .005 |
| No. | 14 | 8 | 16 | — |
| . | Young . | Middle-aged . | Elderly . | P* . |
|---|---|---|---|---|
| CD4lo in CD4+, %† | 15.0 ± 4.8 | 13.8 ± 6.8 | 29.2 ± 3.1 | < .00003 |
| CD4loin PBLs, % | 5.7 ± 2.1 | 8.2 ± 1.9 | 13.6 ± 2.8 | < .005 |
| No. | 14 | 8 | 16 | — |
Data are expressed as mean ± 95% confidence interval. The age groups are described in “Materials and methods.”
PBLs indicates peripheral blood lymphocytes.
Comparison of the young and elderly groups was done by Student t test.
The proportion of CD4lo cells was determined by means of the phycoerythrin-conjugated Leu-3A (anti-CD4) antibody and fluorescein isothiocyanate–conjugated anti-CD3.