Mpl signaling allows for the differentiation of committed myeloid, erythroid, and megakaryocytic progenitor cells
| Experiment . | CFU-GM . | BFU-E . | CFU-MK . | CFU-Mix . |
|---|---|---|---|---|
| 1 | 176 | 7 | 11 | 6 |
| 2 | 188 | 11 | 6 | 4 |
| Experiment . | CFU-GM . | BFU-E . | CFU-MK . | CFU-Mix . |
|---|---|---|---|---|
| 1 | 176 | 7 | 11 | 6 |
| 2 | 188 | 11 | 6 | 4 |
Marrow cells were transduced with the F36VMpl vector, then plated at a concentration of 3 × 104 cells/mL in methylcellulose containing AP20187 (100 nM) without added cytokines. Results show the number of colonies per 6 × 104transduced marrow cells plated.