Table 2. Significant correlation between... | American Society of Hematology

Table 2.

Significant correlation between clinical characteristics and cytogenetic findings

Characteristic	n	Age, ≥ 50 y	Skin lesion	Hepatosplenomegaly	Pleural effusion and/or ascites	LDH, ≥ 1100 IU/μL	Hypercalcemia	WBC, ≥ 30.0 × 10⁶/L	Absolute abnormal lymphocyte count, ≥ 15.0 × 10⁶/L	Unusual immunophenotype	Acute and lymphoma vs chronic	Survival
Characteristic	n	Age, ≥ 50 y	Skin lesion	Hepatosplenomegaly	Pleural effusion and/or ascites	LDH, ≥ 1100 IU/μL	Hypercalcemia	WBC, ≥ 30.0 × 10⁶/L	Absolute abnormal lymphocyte count, ≥ 15.0 × 10⁶/L	Unusual immunophenotype	Acute and lymphoma vs chronic	< 6 mo	Overall
n		(40)	(18)	(26)	(7)	(27)	(27)	(20)	(16)	(8)	(43/7)	(16)
Ploidy
Aneuploid	(34)										P < .05^*,^†
Breakpoint no. ≥ 6	(21)	P < .05^†				P < .05^†	P < .05^†			P < .01^†	P < .05^*,^†		P < .01^‡
Abnormalities on chromosomes
1p	(12)			P < .05^†	P < .05^†	P < .05^†	P < .05^†					P < .05^†	P < .05^‡
1p22	(5)											P < .05^†	P < .01^‡
1q	(13)	P < .05^†							P < .05^†	P < .05^†			P < .05^‡
1q10-21	(7)					P < .05^†							P < .05^‡
2q	(8)											P < .01^†
3q	(23)		P < .05^†									P < .05^†	P < .01^‡
3q10-12	(11)												P < .05^‡
3q21	(7)												P < .05^‡
6q15	(7)								P < .05^†
7q10-11	(6)							P < .01^†
10p	(8)									P < .05^†
10p13	(5)									P < .01^†
12q	(9)						P < .05^†
14q	(13)					P < .05^†				P < .05^†		P < .05^†
14q32	(5)									P < .05^†		P < .05^†
17q	(5)												P < .01^‡
Deletion abnormalities
del(6q)	(7)				P < .05^†
del(10p)	(8)									P < .05^†

Characteristic	n	Age, ≥ 50 y	Skin lesion	Hepatosplenomegaly	Pleural effusion and/or ascites	LDH, ≥ 1100 IU/μL	Hypercalcemia	WBC, ≥ 30.0 × 10⁶/L	Absolute abnormal lymphocyte count, ≥ 15.0 × 10⁶/L	Unusual immunophenotype	Acute and lymphoma vs chronic	Survival
Characteristic	n	Age, ≥ 50 y	Skin lesion	Hepatosplenomegaly	Pleural effusion and/or ascites	LDH, ≥ 1100 IU/μL	Hypercalcemia	WBC, ≥ 30.0 × 10⁶/L	Absolute abnormal lymphocyte count, ≥ 15.0 × 10⁶/L	Unusual immunophenotype	Acute and lymphoma vs chronic	< 6 mo	Overall
n		(40)	(18)	(26)	(7)	(27)	(27)	(20)	(16)	(8)	(43/7)	(16)
Ploidy
Aneuploid	(34)										P < .05^*,^†
Breakpoint no. ≥ 6	(21)	P < .05^†				P < .05^†	P < .05^†			P < .01^†	P < .05^*,^†		P < .01^‡
Abnormalities on chromosomes
1p	(12)			P < .05^†	P < .05^†	P < .05^†	P < .05^†					P < .05^†	P < .05^‡
1p22	(5)											P < .05^†	P < .01^‡
1q	(13)	P < .05^†							P < .05^†	P < .05^†			P < .05^‡
1q10-21	(7)					P < .05^†							P < .05^‡
2q	(8)											P < .01^†
3q	(23)		P < .05^†									P < .05^†	P < .01^‡
3q10-12	(11)												P < .05^‡
3q21	(7)												P < .05^‡
6q15	(7)								P < .05^†
7q10-11	(6)							P < .01^†
10p	(8)									P < .05^†
10p13	(5)									P < .01^†
12q	(9)						P < .05^†
14q	(13)					P < .05^†				P < .05^†		P < .05^†
14q32	(5)									P < .05^†		P < .05^†
17q	(5)												P < .01^‡
Deletion abnormalities
del(6q)	(7)				P < .05^†
del(10p)	(8)									P < .05^†

n indicates number of cases. See Table 1 for other abbreviations.

Statistically significant in acute and lymphoma subtypes.

Fisher exact test.

Log-rank test.