Summary of SP-IR/FN complexes in the sera of patients with or without BM fibrosis
| Proteins . | BM fibrosis . | No fibrosis . | |||
|---|---|---|---|---|---|
| MF . | IMF . | Non-MPD . | MPD . | Non-MPD . | |
| SP-IR | 15/15 | 10/10 | 6/6* | 0/10 | 0/4 |
| FN | 15/15 | 10/10 | 3/6 | 6/10 | 0/4 |
| Proteins . | BM fibrosis . | No fibrosis . | |||
|---|---|---|---|---|---|
| MF . | IMF . | Non-MPD . | MPD . | Non-MPD . | |
| SP-IR | 15/15 | 10/10 | 6/6* | 0/10 | 0/4 |
| FN | 15/15 | 10/10 | 3/6 | 6/10 | 0/4 |
Serum from each subject was studied for co-immunoprecipitation in duplicate samples for SP-IR and FN. Numerators represent the number of positive bands among the total number in a particular category of patients, shown in denominators. Representative Western blots are shown in Figure 4. Because immunoprecipitation was performed with anti-SP, the zero for FN indicates that it was not complexed to SP.
SP-IR in 3 samples was detected at the predicted size.