Total number (×103) of progenitor and precursor cells in the spleen of wild-type and GATA-1lowmice
| . | Progenitor cells . | Precursor cells . | ||||
|---|---|---|---|---|---|---|
| CFU-GM . | BFU-E . | CFU-E . | TER-119+/4A5+ . | TER-119+ . | 4A5+ . | |
| Wild-type | ||||||
| Untreated | 182 | 110 | 178 | 1280 | 3500 | 600 |
| Day-1 PHZ | 243 | 697 | 1130 | 13 900 | 49 500 | 7600 |
| Day-6 EPO | 472 | 3500 | 1590 | 2200 | 442 000 | 6700 |
| GATA-1low | ||||||
| Untreated | 275 | 762 | 4200 | 37 500 | 84 200 | 48 700 |
| Day-1 PHZ | 617 | 4179 | 30 450 | 273 000 | 756 000 | 201 000 |
| Day-6 EPO | 980 | 20 700 | 17 000 | 22 500 | 1 625 000 | 45 000 |
| . | Progenitor cells . | Precursor cells . | ||||
|---|---|---|---|---|---|---|
| CFU-GM . | BFU-E . | CFU-E . | TER-119+/4A5+ . | TER-119+ . | 4A5+ . | |
| Wild-type | ||||||
| Untreated | 182 | 110 | 178 | 1280 | 3500 | 600 |
| Day-1 PHZ | 243 | 697 | 1130 | 13 900 | 49 500 | 7600 |
| Day-6 EPO | 472 | 3500 | 1590 | 2200 | 442 000 | 6700 |
| GATA-1low | ||||||
| Untreated | 275 | 762 | 4200 | 37 500 | 84 200 | 48 700 |
| Day-1 PHZ | 617 | 4179 | 30 450 | 273 000 | 756 000 | 201 000 |
| Day-6 EPO | 980 | 20 700 | 17 000 | 22 500 | 1 625 000 | 45 000 |
The values are calculated from those presented in Table 1 and Figure 3.
PHZ indicates phenylhydrazine; EPO, erythropoietin. For explanation of other abbreviations, see footnote to Table 2.