Comparison of causes of death for recipients of 0-3 HLA–mismatched umbilical cord blood versus human leukocyte antigen–matched bone marrow
Cause of death . | UCB n = 11 . | BM-MTX n = 15 . | UCB n = 13 . | BM-TCD n = 14 . |
---|---|---|---|---|
GVHD +/− infection | 4 (36%) | 5 (33%) | 3 (23%) | 7 (50%) |
Relapse/refractory leukemia | 5 (45%) | 4 (27%) | 3 (23%) | 1 (7%) |
Graft failure | 0 (0%) | 0 (0%) | 2 (15%) | 2 (14%) |
Organ failure +/− infection | 1 (9%) | 4 (27%) | 1 (8%) | 0 (0%) |
Other | 1 (9%) | 2 (13%) | 4 (31%) | 4 (29%) |
Cause of death . | UCB n = 11 . | BM-MTX n = 15 . | UCB n = 13 . | BM-TCD n = 14 . |
---|---|---|---|---|
GVHD +/− infection | 4 (36%) | 5 (33%) | 3 (23%) | 7 (50%) |
Relapse/refractory leukemia | 5 (45%) | 4 (27%) | 3 (23%) | 1 (7%) |
Graft failure | 0 (0%) | 0 (0%) | 2 (15%) | 2 (14%) |
Organ failure +/− infection | 1 (9%) | 4 (27%) | 1 (8%) | 0 (0%) |
Other | 1 (9%) | 2 (13%) | 4 (31%) | 4 (29%) |
The “other” category included infection alone, progressive disease of an inborn error of metabolism, or Epstein-Barr virus–associated lymphoproliferative disease. For abbreviations, see Tables 1 and 2.