Table 3.

Comparison of causes of death for recipients of 0-3 HLA–mismatched umbilical cord blood versus human leukocyte antigen–matched bone marrow

Cause of deathUCB n = 11BM-MTX n = 15UCB n = 13BM-TCD n = 14
GVHD +/− infection 4  (36%) 5  (33%) 3  (23%) 7  (50%)  
Relapse/refractory leukemia 5  (45%) 4  (27%) 3  (23%) 1  (7%) 
Graft failure 0  (0%) 0  (0%) 2  (15%) 2  (14%) 
Organ failure +/− infection 1  (9%) 4  (27%) 1  (8%) 0  (0%)  
Other 1  (9%) 2  (13%) 4  (31%) 4  (29%) 
Cause of deathUCB n = 11BM-MTX n = 15UCB n = 13BM-TCD n = 14
GVHD +/− infection 4  (36%) 5  (33%) 3  (23%) 7  (50%)  
Relapse/refractory leukemia 5  (45%) 4  (27%) 3  (23%) 1  (7%) 
Graft failure 0  (0%) 0  (0%) 2  (15%) 2  (14%) 
Organ failure +/− infection 1  (9%) 4  (27%) 1  (8%) 0  (0%)  
Other 1  (9%) 2  (13%) 4  (31%) 4  (29%) 

The “other” category included infection alone, progressive disease of an inborn error of metabolism, or Epstein-Barr virus–associated lymphoproliferative disease. For abbreviations, see Tables 1 and 2.

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