Table 4. Proviral DNA, viral RNA, and... | American Society of Hematology

Table 4.

Proviral DNA, viral RNA, and spliced viral mRNA in bulk cells and in the white pulps and germinal centers

Patient	B	C	R	K
Frequency of DNA+ cells^3-150	>1/50	1/2700	1/3800	1/175
Bulk cells^3-151
DNA (env V1V2)	+	+	+	+
RNA (env V1V2)	+	+	+	+
Spliced RNA (env mRNA)	−	−	−	−
White pulps, germinal centers^3-152
DNA (env V1V2)	5/5	7/9	8/8	9/9
RNA (env V1V2)	5/5	0/4	2/5	2/2
Spliced RNA (env mRNA)	4/5	0/4	0/5	2/2

Patient	B	C	R	K
Frequency of DNA+ cells^3-150	>1/50	1/2700	1/3800	1/175
Bulk cells^3-151
DNA (env V1V2)	+	+	+	+
RNA (env V1V2)	+	+	+	+
Spliced RNA (env mRNA)	−	−	−	−
White pulps, germinal centers^3-152
DNA (env V1V2)	5/5	7/9	8/8	9/9
RNA (env V1V2)	5/5	0/4	2/5	2/2
Spliced RNA (env mRNA)	4/5	0/4	0/5	2/2

Limiting-dilution PCR on bulk SMCs or TMCs.

Data are given as positive or negative PCR results from 2 × 10⁵ cell extracts (bulk cells).

Positive white pulps/total number of white pulps (or germinal centers) tested (ND indicates not determined).