Table 2.

Phenotype of cells from the lymphoid organs of the patients (% positive cells)

Lymphoid organPatient B SpleenPatient C SpleenPatient R SpleenPatient mean, SD SpleensHIV-negative controls Spleens
n = 8
Patient K* Tonsils
CD3+ 68 49 82 66 ± 14 36 ± 18 55 
CD19+ 19 24 16 ± 8 52 ± 18 32 
CD4+CD3+ 19 16 13 16 ± 2 14 ± 8 27 
CD8+CD3+ 48 30 66 48 ± 15 15 ± 8 27 
CD45RO+/CD8 47 58 32 46 ± 11 24 ± 6 42 
CD45RA+/CD8 19 30 45 31 ± 11 55 ± 27 34 
CD25+/CD8 2 ± 0 ND 
CD38+/CD8 34 27 63 41 ± 16 28 ± 14 44 
HLA-DR+/CD8 27 17 31 25 ± 6 13 ± 20 16 
TiA1+/CD8 33 14 42 30 ± 12 76 ± 23 20 
Lymphoid organPatient B SpleenPatient C SpleenPatient R SpleenPatient mean, SD SpleensHIV-negative controls Spleens
n = 8
Patient K* Tonsils
CD3+ 68 49 82 66 ± 14 36 ± 18 55 
CD19+ 19 24 16 ± 8 52 ± 18 32 
CD4+CD3+ 19 16 13 16 ± 2 14 ± 8 27 
CD8+CD3+ 48 30 66 48 ± 15 15 ± 8 27 
CD45RO+/CD8 47 58 32 46 ± 11 24 ± 6 42 
CD45RA+/CD8 19 30 45 31 ± 11 55 ± 27 34 
CD25+/CD8 2 ± 0 ND 
CD38+/CD8 34 27 63 41 ± 16 28 ± 14 44 
HLA-DR+/CD8 27 17 31 25 ± 6 13 ± 20 16 
TiA1+/CD8 33 14 42 30 ± 12 76 ± 23 20 
*

Data from the tonsils are given for information, but they were not compared with normal controls.

CD45RO, CD45RA, CD25, CD38, HLA-DR, and TiA1 were analyzed on the CD8+ population.

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