Table 1. Patients and BLPD... | American Society of Hematology

Table 1.

Patients and BLPD characteristics

Patient/sex	Age (y)	Disease	Transplant	Affected sites	General manifestations	Pathologic morphology of BLPD lesions	Phenotype of infiltrating cells in BLPD lesions	Clonality of BLPD lesions	EBV in BLPD lesions	Detection of EBV genome by PCR out of tumor site	Circulating B cells (CD19 or CD20/μl)
1/F	41	Lymphoangiomatosis	Unipulmonary	Endobronchial	None	Polymorphic necrosis	CD20⁺	Polyclonal	LMP1⁺ EBER⁺	ND	80
2/M	61	OLD	Bipulmonary	Bone, bone marrow, pleura, mediastinal nodes	Fever, high CRP level	Monomorphic, plasmacytoid	IgA_κ⁺	Polyclonal	EBER⁺	ND	ND^*
3/M	33	Renal artery trauma	Kidney	Lymph nodes, liver	Fever, high CRP level	Polymorphic	CD20⁺ CD79⁺ CD30⁺	ND	LMP1⁺	Blood	6
4/F	27	Pulmonary hypertension	Bipulmonary	Oral	None	Monomorphic necrosis	CD30⁺	Monoclonal	LMP1⁺ EBER⁺	ND	20
5/M	38	Cystic fibrosis	Bipulmonary	Lungs	None	Polymorphic necrosis	CD20⁺ CD79⁺	ND	LMP1⁺ EBER⁺	Blood bone marrow CSF	92
6/M	62	Liver cirrhosis	Liver	Liver hilum	High CRP level	Polymorphic necrosis	CD20⁺ CD79⁺	Polyclonal	LMP1⁺	Blood	14
7/M	49	NOCM	Heart	Perinephritis, cutaneous	High CRP level	Monomorphic plasmacytoid	κ chain⁺	Monoclonal	Southern⁺ PCR⁺	ND	ND^*
8/M	1	Biliary atresia	Liver	Liver, spleen, lymph nodes pleura	Fever, high CRP level	Polymorphic	CD20⁺	Monoclonal	PCR⁺	Blood, CSF,	40
9/M	12	α₁Anti-trypsine deficiency	Liver	Liver hilum, graft (liver), bone marrow	Fever, high CRP level	Polymorphic necrosis	CD19⁺ CD20⁺ CD22⁺	Monoclonal	EBER⁺ PCR⁺	Pleursy blood, bone marrow	45
10/M	31	Interstitial nephritis	Kidney	Liver, abdomen, lymph nodes, subcutaneous	High CRP level	Polymorphic	CD20⁺ CD79⁺	ND	LMP1⁺	Blood	ND
11/M	32	Kidney hypoplasia	Kidney	Graft (kidney), kidney hilum, lymph nodes	Fever, high CRP level	Polymorphic	CD20⁺	ND	LMP1⁺ EBER⁺	ND	7
12/M	20	Cystic fibrosis	Bipulmonary	Lungs, mediastinal nodes	High CRP level	Polymorphic necrosis	CD19⁺ CD20⁺ CD79⁺	Monoclonal	LMP1⁺ EBER⁺	Blood	None

Patient/sex	Age (y)	Disease	Transplant	Affected sites	General manifestations	Pathologic morphology of BLPD lesions	Phenotype of infiltrating cells in BLPD lesions	Clonality of BLPD lesions	EBV in BLPD lesions	Detection of EBV genome by PCR out of tumor site	Circulating B cells (CD19 or CD20/μl)
1/F	41	Lymphoangiomatosis	Unipulmonary	Endobronchial	None	Polymorphic necrosis	CD20⁺	Polyclonal	LMP1⁺ EBER⁺	ND	80
2/M	61	OLD	Bipulmonary	Bone, bone marrow, pleura, mediastinal nodes	Fever, high CRP level	Monomorphic, plasmacytoid	IgA_κ⁺	Polyclonal	EBER⁺	ND	ND^*
3/M	33	Renal artery trauma	Kidney	Lymph nodes, liver	Fever, high CRP level	Polymorphic	CD20⁺ CD79⁺ CD30⁺	ND	LMP1⁺	Blood	6
4/F	27	Pulmonary hypertension	Bipulmonary	Oral	None	Monomorphic necrosis	CD30⁺	Monoclonal	LMP1⁺ EBER⁺	ND	20
5/M	38	Cystic fibrosis	Bipulmonary	Lungs	None	Polymorphic necrosis	CD20⁺ CD79⁺	ND	LMP1⁺ EBER⁺	Blood bone marrow CSF	92
6/M	62	Liver cirrhosis	Liver	Liver hilum	High CRP level	Polymorphic necrosis	CD20⁺ CD79⁺	Polyclonal	LMP1⁺	Blood	14
7/M	49	NOCM	Heart	Perinephritis, cutaneous	High CRP level	Monomorphic plasmacytoid	κ chain⁺	Monoclonal	Southern⁺ PCR⁺	ND	ND^*
8/M	1	Biliary atresia	Liver	Liver, spleen, lymph nodes pleura	Fever, high CRP level	Polymorphic	CD20⁺	Monoclonal	PCR⁺	Blood, CSF,	40
9/M	12	α₁Anti-trypsine deficiency	Liver	Liver hilum, graft (liver), bone marrow	Fever, high CRP level	Polymorphic necrosis	CD19⁺ CD20⁺ CD22⁺	Monoclonal	EBER⁺ PCR⁺	Pleursy blood, bone marrow	45
10/M	31	Interstitial nephritis	Kidney	Liver, abdomen, lymph nodes, subcutaneous	High CRP level	Polymorphic	CD20⁺ CD79⁺	ND	LMP1⁺	Blood	ND
11/M	32	Kidney hypoplasia	Kidney	Graft (kidney), kidney hilum, lymph nodes	Fever, high CRP level	Polymorphic	CD20⁺	ND	LMP1⁺ EBER⁺	ND	7
12/M	20	Cystic fibrosis	Bipulmonary	Lungs, mediastinal nodes	High CRP level	Polymorphic necrosis	CD19⁺ CD20⁺ CD79⁺	Monoclonal	LMP1⁺ EBER⁺	Blood	None

OLD, obstructive lung disease; NOCM, nonobstructive cardiomyopathy; CSF, cerebrospinal fluid.

In 2 patients, hyperbasophilic cells could be detected in blood.