Table 3. Cytotoxic activity of / , mi /... | American Society of Hematology

Table 3.

Cytotoxic activity of +/+, mi/mi,mi^ce/mi^ce, andtg/tg CMCs to YAC-1 cells

E:T ratio	Specific ⁵¹Cr release, %^3-150
E:T ratio	+/+ CMCs	Mi/MiCMCs	mi^ce/mi^ceCMCs	tg/tg CMCs	+/+ spleen cells
50	< 0.1	< 0.1	< 0.1	< 0.1	52.2 ± 3.8^3-151
100	12.8 ± 0.2^3-151	< 0.1	10.1 ± 0.3^3-151	11.9 ± 0.6^3-151	58.3 ± 5.2^3-151
250	25.2 ± 2.4^3-151	< 0.1	16.6 ± 2.3^3-151	19.1 ± 1.6^3-151	NE

E:T ratio	Specific ⁵¹Cr release, %^3-150
E:T ratio	+/+ CMCs	Mi/MiCMCs	mi^ce/mi^ceCMCs	tg/tg CMCs	+/+ spleen cells
50	< 0.1	< 0.1	< 0.1	< 0.1	52.2 ± 3.8^3-151
100	12.8 ± 0.2^3-151	< 0.1	10.1 ± 0.3^3-151	11.9 ± 0.6^3-151	58.3 ± 5.2^3-151
250	25.2 ± 2.4^3-151	< 0.1	16.6 ± 2.3^3-151	19.1 ± 1.6^3-151	NE

E:T ratio is the ratio of CMCs or spleen cells to YAC-1 cells.

NE indicates not examined.

Mean ± SE of 3 experiments.

P < .01 by t test compared with the value of mi/mi CMCs.