Results of Protocol 91-01 for 377 children with ALL
| . | Total . | SR . | HR . |
|---|---|---|---|
| Patients | |||
| Total, no. | 377 | 137 | 240 |
| Total, % | 100 | 36 | 64 |
| Induction, no. | |||
| Failures | 5 | 0 | 5 |
| Deaths | 2 | 0 | 2 |
| Complete remissions | |||
| Total, no. | 370 | 137 | 233 |
| Total, % | 98 | 100 | 97 |
| Relapse, no. | 46 | 16 | 30 |
| BM only | 31 | 12 | 19 |
| CNS only | 4 | 1 | 3 |
| CNS + BM | 8 | 3 | 5 |
| Testis | 2 | 0 | 2 |
| Testis + BM | 1 | 0 | 1 |
| Remission, no. | |||
| Deaths | 12 | 4 | 8 |
| Continuous3-150 | 312 | 117 | 195 |
| 5-y ± SE, % | |||
| EFS | 83 ± 2 | 87 ± 3 | 81 ± 3 |
| LFS | 87 ± 2 | 90 ± 3 | 85 ± 2 |
| OS | 88 ± 2 | 92 ± 2 | 86 ± 2 |
| . | Total . | SR . | HR . |
|---|---|---|---|
| Patients | |||
| Total, no. | 377 | 137 | 240 |
| Total, % | 100 | 36 | 64 |
| Induction, no. | |||
| Failures | 5 | 0 | 5 |
| Deaths | 2 | 0 | 2 |
| Complete remissions | |||
| Total, no. | 370 | 137 | 233 |
| Total, % | 98 | 100 | 97 |
| Relapse, no. | 46 | 16 | 30 |
| BM only | 31 | 12 | 19 |
| CNS only | 4 | 1 | 3 |
| CNS + BM | 8 | 3 | 5 |
| Testis | 2 | 0 | 2 |
| Testis + BM | 1 | 0 | 1 |
| Remission, no. | |||
| Deaths | 12 | 4 | 8 |
| Continuous3-150 | 312 | 117 | 195 |
| 5-y ± SE, % | |||
| EFS | 83 ± 2 | 87 ± 3 | 81 ± 3 |
| LFS | 87 ± 2 | 90 ± 3 | 85 ± 2 |
| OS | 88 ± 2 | 92 ± 2 | 86 ± 2 |
HR includes HR patients and infant HR patients. See Table 1 and Table 2 for abbreviations.
Median follow-up time was 5.0 years.