Selected candidate genes identified by the microarray approach
| Balanced difference factor . | Gene . | Abbreviation . |
|---|---|---|
| +19.5 | Plasminogen activator inhibitor 2 | PAI-2 |
| +7.9 | Interferon-induced cell line protein 10 | IP-10 |
| +4.0 | Neutrophil defensins 1, 2, and 3 | nd |
| +3.8 | FcγRIII | CD16 |
| +3.2 | Monocyte chemotactic protein 1 | MCP-1 |
| −3.0 | C-C chemokine receptor type 2 | CCR2 |
| +3.0 | C3a anaphylatoxin receptor | C3aR |
| +2.7 | Adipophilin | nd |
| Balanced difference factor . | Gene . | Abbreviation . |
|---|---|---|
| +19.5 | Plasminogen activator inhibitor 2 | PAI-2 |
| +7.9 | Interferon-induced cell line protein 10 | IP-10 |
| +4.0 | Neutrophil defensins 1, 2, and 3 | nd |
| +3.8 | FcγRIII | CD16 |
| +3.2 | Monocyte chemotactic protein 1 | MCP-1 |
| −3.0 | C-C chemokine receptor type 2 | CCR2 |
| +3.0 | C3a anaphylatoxin receptor | C3aR |
| +2.7 | Adipophilin | nd |
Known genes with a high-balanced difference factor were selected for further investigations. The plus sign for the balanced difference factor indicates a higher expression in patient monocytes when compared with the control. A minus sign indicates suppression of this gene in the patient monocytes.
nd indicates not defined.