Interaction between activated protein C resistance and lupus anticoagulants in their association with thrombotic events
| APCR . | LA . | TE positive . | TE negative . | Risk (%) . | RD (%) (95% CI) . | P . |
|---|---|---|---|---|---|---|
| Positive | Positive | 7 | 3 | 70 | 70 (28-90) | .004 |
| Negative | 0 | 8 | 0 | |||
| Negative | Positive | 2 | 8 | 20 | 20 (−6-52) | .06 |
| Negative | 0 | 30 | 0 |
| APCR . | LA . | TE positive . | TE negative . | Risk (%) . | RD (%) (95% CI) . | P . |
|---|---|---|---|---|---|---|
| Positive | Positive | 7 | 3 | 70 | 70 (28-90) | .004 |
| Negative | 0 | 8 | 0 | |||
| Negative | Positive | 2 | 8 | 20 | 20 (−6-52) | .06 |
| Negative | 0 | 30 | 0 |
Risk difference model: APCR × LA interaction: χ score(1)2 4.2; P = .04.
APCR indicates activated protein C resistance; LA, lupus anticoagulants; TE, thrombotic event; RD, risk difference; CI, confidence interval.