Table 2. IL-6 levels and disease... | American Society of Hematology

Table 2.

IL-6 levels and disease characteristics (n = 151)

Category	No. patients	Median IL-6 (pg/mL) (range)	P value^*
β₂-microglobulin (mg/L)¹
<2	24	<0.91 (<0.91-11)	<.001
≥2	104	1.93 (<0.91-110)
Previous treatment
Yes	89	2.16 (<0.91-110)	.0004
No	62	<0.91 (<0.91-37)
Serum LDH level (IU/mL)^†
≥618	24	2.91 (<0.91-74)	.02
<618	112	1.20 (<0.91-110)
Rai stage
0, I, II	124	1.04 (<0.91-110)	.0001
III, IV	27	2.94 (<0.91-51)
Age (y)
<60	77	<0.091 (<0.91-80)	.003
≥60	74	2.01 (<0.91-110)

Category	No. patients	Median IL-6 (pg/mL) (range)	P value^*
β₂-microglobulin (mg/L)¹
<2	24	<0.91 (<0.91-11)	<.001
≥2	104	1.93 (<0.91-110)
Previous treatment
Yes	89	2.16 (<0.91-110)	.0004
No	62	<0.91 (<0.91-37)
Serum LDH level (IU/mL)^†
≥618	24	2.91 (<0.91-74)	.02
<618	112	1.20 (<0.91-110)
Rai stage
0, I, II	124	1.04 (<0.91-110)	.0001
III, IV	27	2.94 (<0.91-51)
Age (y)
<60	77	<0.091 (<0.91-80)	.003
≥60	74	2.01 (<0.91-110)

IL-6 indicates interleukin 6; LDH, lactate dehydrogenase.

Using the Mann-Whitney test.

Upper limit of normal for LDH at M. D. Anderson Cancer Center is 618 IU/mL.