Comparison of treatment outcomes among subgroups of unfavorable risk category
| −5/5qånd/or −7/7q− . | Complex karyotype . | No. of patients . | CR rate . | Overall survival . | ||||
|---|---|---|---|---|---|---|---|---|
| Probability of surviving 2 years . | Relative risk . | |||||||
| CR(%)5-150 . | 95% CI . | Probability (%) . | 95% CI . | RR . | 95% CI . | |||
| No | No | 90 | 68 | 58-78 | 27 | 19-37 | 1.00 | — |
| Yes | 30 | 50 | 31-69 | 20 | 8-39 | 1.29 | 0.83-2.00 | |
| Yes | No | 31 | 43 | 26-61 | 19 | 7-37 | 1.27 | 0.81-1.98 |
| Yes | 33 | 37 | 19-54 | 3 | 0-16 | 2.40 | 1.58-3.64 | |
| −5/5qånd/or −7/7q− . | Complex karyotype . | No. of patients . | CR rate . | Overall survival . | ||||
|---|---|---|---|---|---|---|---|---|
| Probability of surviving 2 years . | Relative risk . | |||||||
| CR(%)5-150 . | 95% CI . | Probability (%) . | 95% CI . | RR . | 95% CI . | |||
| No | No | 90 | 68 | 58-78 | 27 | 19-37 | 1.00 | — |
| Yes | 30 | 50 | 31-69 | 20 | 8-39 | 1.29 | 0.83-2.00 | |
| Yes | No | 31 | 43 | 26-61 | 19 | 7-37 | 1.27 | 0.81-1.98 |
| Yes | 33 | 37 | 19-54 | 3 | 0-16 | 2.40 | 1.58-3.64 | |
CR indicates complete remission; CI, confidence interval; RR, relative risk.
Response was unknown for 11 patients: 1 with −5/5q− and/or −7/7q− only, 2 with complex only, 5 with neither, and 3 with both.