Clinical features of patients investigated
| Experiment no. . | Patient . | Age . | Sex . | Platelets (×10−9/L) . | Spleen enlarged? . | Cytokine sensitivity ratio/presumptive diagnosis . | |||
|---|---|---|---|---|---|---|---|---|---|
| ET . | 2°T . | PV . | Rx . | ||||||
| 155/9 | PP | 54 | M | 783 | No | 40× | None | ||
| 156 | RF | 80 | F | 294 | No | Low, flat | HU | ||
| 160 | DM | 71 | F | 1129 | No | 92.5× | ASA | ||
| 160 | WSC | 78 | M | 462 | Slightly | Low, flat | None | ||
| 161 | LB | 75 | M | 903 | Yes, rupt. | 31.1× (and mfb) | Splx, HU, ASA | ||
| 164 | RL | 75 | F | 832 | No | 33.3× (and CVA, ht) | ASA | ||
| 169 | VL | 36 | M | 1291 | No | high, flat | None | ||
| 170 | EF | 49 | F | 737 | No | > 525× | None | ||
| 172 | RB | 72 | M | 391 | No | 0.9× (and MGUS) | ASA | ||
| 175 | AB | 73 | F | 714 | No | 66.7× | None | ||
| 177 | LS | 75 | M | 301 | No | 0.9× (and ca, hpot, as) | HU, ASA | ||
| 179 | EG | 27 | F | 517 | No | High, flat | P-C shunt | ||
| 188 | PN | 71 | F | 525 | No | 1.1× (and hpot) | ASA | ||
| 191 | CM | 48 | M | 566 | Atrophic | 1.1× (sca, tca) | HU | ||
| 192 | RA | 21 | M | 167 | Yes | High, flat | None | ||
| 197 | JP | 34 | F | 428 | Atrophic | High, flat (and sca) | None | ||
| 198 | JH | 42 | F | 1487 | No | 0.7× (and ca cecum) | None | ||
| 200 | SS | 63 | F | 712 | Infarcts | 0.4× (and bladder ca) | None | ||
| 201 | BKK | 42 | M | 847 | Removed | 200× | None | ||
| 209 | SS | 48 | M | 797 | Yes | 26.7× (and β thal min) | None | ||
| 210 | LSY | 76 | F | 1724 | No | 181.1× (and iron def an) | HU, ASA | ||
| 212 | NG | 74 | M | 800 | Slightly | 21.7× (and hchol, ht, pulc) | HU, ASA | ||
| 217 | KC | 51 | M | 912 | No | 718.8× (and hchol, ht, pulc) | HU, ASA | ||
| 218 | DD | 64 | F | 296 | No | > 456× (and hpot, Dm, GERD, osteop) | HU, ASA | ||
| 221 | EK | 75 | F | 698 | Yes | > 425× (and Dm, CHF) | HU, ASA | ||
| 225 | BD | 67 | F | 491 | No | low, flat | None | ||
| 227 | MT | 82 | M | 535 | No | 173.3× (and ht, AMI, SBO) | HU, ASA | ||
| 230 | RB | 70 | F | 905 | No | 64× | None | ||
| 233 | MS | 73 | F | 1258 | No | 1.0× (and sidero an) | None | ||
| 234 | EG | 57 | F | 433 | Yes, infarct | 1.1× (and hydroneph) | Splx | ||
| 238 | OEP | 65 | M | 2567 | No, acc spl | 0.4× (and ht, an, αthal) | None | ||
| 240 | IK | 62 | F | 1152 | No | 1.0× (and an, hpot) | None | ||
| 242 | MD | 77 | F | 884 | No | High, flat (and Parkins) | None | ||
| 243 | SYF | 49 | F | 1022 | No | High, flat (and an, Hep B) | None | ||
| 244 | EC | 64 | M | 1149 | Slightly | 53.3× (and cholelith) | ASA | ||
| 249 | MW | 70 | F | 632 | No | low, flat | ASA | ||
| 250 | BH | 49 | M | 482 | No | High, flat (and Hep B, CVA) | ASA | ||
| 251 | MO | 68 | M | 738 | No | 1.3× (and AMI) | ASA, b/p | ||
| 252 | CF | 83 | M | 206 | Markedly | 0.9× (and hydroneph, DVT) | b, HU | ||
| 255 | DS | 49 | F | 577 | Slightly | > 12.5× | None | ||
| 257 | GG | 76 | F | 754 | No | > 8× (and br ca) | HU, ASA | ||
| 262 | SW | 36 | F | 601 | No | 13.5× (and iron def an) | ASA | ||
| 267 | TS | 67 | M | 1600 | No | > 250×* | ASA | ||
| Experiment no. . | Patient . | Age . | Sex . | Platelets (×10−9/L) . | Spleen enlarged? . | Cytokine sensitivity ratio/presumptive diagnosis . | |||
|---|---|---|---|---|---|---|---|---|---|
| ET . | 2°T . | PV . | Rx . | ||||||
| 155/9 | PP | 54 | M | 783 | No | 40× | None | ||
| 156 | RF | 80 | F | 294 | No | Low, flat | HU | ||
| 160 | DM | 71 | F | 1129 | No | 92.5× | ASA | ||
| 160 | WSC | 78 | M | 462 | Slightly | Low, flat | None | ||
| 161 | LB | 75 | M | 903 | Yes, rupt. | 31.1× (and mfb) | Splx, HU, ASA | ||
| 164 | RL | 75 | F | 832 | No | 33.3× (and CVA, ht) | ASA | ||
| 169 | VL | 36 | M | 1291 | No | high, flat | None | ||
| 170 | EF | 49 | F | 737 | No | > 525× | None | ||
| 172 | RB | 72 | M | 391 | No | 0.9× (and MGUS) | ASA | ||
| 175 | AB | 73 | F | 714 | No | 66.7× | None | ||
| 177 | LS | 75 | M | 301 | No | 0.9× (and ca, hpot, as) | HU, ASA | ||
| 179 | EG | 27 | F | 517 | No | High, flat | P-C shunt | ||
| 188 | PN | 71 | F | 525 | No | 1.1× (and hpot) | ASA | ||
| 191 | CM | 48 | M | 566 | Atrophic | 1.1× (sca, tca) | HU | ||
| 192 | RA | 21 | M | 167 | Yes | High, flat | None | ||
| 197 | JP | 34 | F | 428 | Atrophic | High, flat (and sca) | None | ||
| 198 | JH | 42 | F | 1487 | No | 0.7× (and ca cecum) | None | ||
| 200 | SS | 63 | F | 712 | Infarcts | 0.4× (and bladder ca) | None | ||
| 201 | BKK | 42 | M | 847 | Removed | 200× | None | ||
| 209 | SS | 48 | M | 797 | Yes | 26.7× (and β thal min) | None | ||
| 210 | LSY | 76 | F | 1724 | No | 181.1× (and iron def an) | HU, ASA | ||
| 212 | NG | 74 | M | 800 | Slightly | 21.7× (and hchol, ht, pulc) | HU, ASA | ||
| 217 | KC | 51 | M | 912 | No | 718.8× (and hchol, ht, pulc) | HU, ASA | ||
| 218 | DD | 64 | F | 296 | No | > 456× (and hpot, Dm, GERD, osteop) | HU, ASA | ||
| 221 | EK | 75 | F | 698 | Yes | > 425× (and Dm, CHF) | HU, ASA | ||
| 225 | BD | 67 | F | 491 | No | low, flat | None | ||
| 227 | MT | 82 | M | 535 | No | 173.3× (and ht, AMI, SBO) | HU, ASA | ||
| 230 | RB | 70 | F | 905 | No | 64× | None | ||
| 233 | MS | 73 | F | 1258 | No | 1.0× (and sidero an) | None | ||
| 234 | EG | 57 | F | 433 | Yes, infarct | 1.1× (and hydroneph) | Splx | ||
| 238 | OEP | 65 | M | 2567 | No, acc spl | 0.4× (and ht, an, αthal) | None | ||
| 240 | IK | 62 | F | 1152 | No | 1.0× (and an, hpot) | None | ||
| 242 | MD | 77 | F | 884 | No | High, flat (and Parkins) | None | ||
| 243 | SYF | 49 | F | 1022 | No | High, flat (and an, Hep B) | None | ||
| 244 | EC | 64 | M | 1149 | Slightly | 53.3× (and cholelith) | ASA | ||
| 249 | MW | 70 | F | 632 | No | low, flat | ASA | ||
| 250 | BH | 49 | M | 482 | No | High, flat (and Hep B, CVA) | ASA | ||
| 251 | MO | 68 | M | 738 | No | 1.3× (and AMI) | ASA, b/p | ||
| 252 | CF | 83 | M | 206 | Markedly | 0.9× (and hydroneph, DVT) | b, HU | ||
| 255 | DS | 49 | F | 577 | Slightly | > 12.5× | None | ||
| 257 | GG | 76 | F | 754 | No | > 8× (and br ca) | HU, ASA | ||
| 262 | SW | 36 | F | 601 | No | 13.5× (and iron def an) | ASA | ||
| 267 | TS | 67 | M | 1600 | No | > 250×* | ASA | ||
acc spl, accessory spleen; α thal, α thalassemia; AMI, acute myocardial infarction; ASA, acetylsalicylic acid; β thal min, β thalassemia minor; b/p, busulfan/in the past; ca, carcinoma; CHF, congestive heart failure; CVA, cerebrovascular accident; cholelith, cholelithiasis; Dm, Diabetes mellitus; DVT, deep vein thrombosis; gastr lym, gastric lymphoma; GERD, gastroesophageal reflux disorder; Hep B, Hepatitis B; hpot, hypothyroidism; hydronephr, hydronephrosis; HU, Hydroxyurea; ht, hypertension; mfb, myelofibrosis; MGUS, monoclonal gammopathy of undetermined significance; mpd, myeloproliferative disorder; osteop, osteopenia; Parkins, Parkinson disease; p-c shunt, porta-caval shunt for Budd-Chiari syndrome; pulc, peptic ulcer; Rx, treatment with platelet lowering agent(s); SBO, small bowel obstruction; sca, sickle cell anemia; 2°T, secondary thrombocytosis; sidero an, sideroblastic anemia; splx, splenectomy; tca, thyroid carcinoma.
Nonadherent cells only.