Table 1.

Characteristics and composition of o-raffinose cross-linked hemoglobin supplied by the manufacturer

VariableValue
Total hemoglobin concentration, g/L 10  
Molecular weight distribution, %*  
 32 kd 2.6  
 64 kd 28.1  
 > 64 to 500 kd 68.2  
 > 500 kd 1.2  
Methemoglobin, % 4.2  
Partial pressure of oxygen at which hemoglobin is 50% saturated, mm Hg 40  
Colloid osmotic pressure, mm Hg 22.4  
Endotoxin, endotoxin U/mL on limulus amebocyte lysate assay < 0.06 
VariableValue
Total hemoglobin concentration, g/L 10  
Molecular weight distribution, %*  
 32 kd 2.6  
 64 kd 28.1  
 > 64 to 500 kd 68.2  
 > 500 kd 1.2  
Methemoglobin, % 4.2  
Partial pressure of oxygen at which hemoglobin is 50% saturated, mm Hg 40  
Colloid osmotic pressure, mm Hg 22.4  
Endotoxin, endotoxin U/mL on limulus amebocyte lysate assay < 0.06 
*

 Extent of polymerization as determined by size-exclusion chromatography under dissociating conditions.

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