Patient demographic data
. | Cohort 1 (N = 10) N . | Cohort 2 (N = 11) N . |
---|---|---|
No. patients with ER/PR+ tumors | 4 | 4 |
No. patients with ER/PR− tumors | 6 | 7 |
No. patients with prior radiation Rx | 2 | 2 |
Mean no. prior ChemRx cycles | 5 | 4 |
Phase II, CCT* or CCB | 8 | 11 |
Stage II 4-9+ nodes | 1 | 2 |
Stage II 10+ nodes | 4 | 3 |
Stage III, inflammatory | 1* | 1* |
Stage IV, measurable | 0 | 2 |
Stage IV, NED | 2 (1*) | 3 |
Phase 1, TCM | 2 | 0 |
Stage IV, measurable | 2 | 0 |
. | Cohort 1 (N = 10) N . | Cohort 2 (N = 11) N . |
---|---|---|
No. patients with ER/PR+ tumors | 4 | 4 |
No. patients with ER/PR− tumors | 6 | 7 |
No. patients with prior radiation Rx | 2 | 2 |
Mean no. prior ChemRx cycles | 5 | 4 |
Phase II, CCT* or CCB | 8 | 11 |
Stage II 4-9+ nodes | 1 | 2 |
Stage II 10+ nodes | 4 | 3 |
Stage III, inflammatory | 1* | 1* |
Stage IV, measurable | 0 | 2 |
Stage IV, NED | 2 (1*) | 3 |
Phase 1, TCM | 2 | 0 |
Stage IV, measurable | 2 | 0 |
ER, estrogen receptor; PR, progesterone receptor; Rx, therapy; NED, no evidence of disease; TCM, taxotere-carboplatin.
Received CCT (cyclophosphamide-cisplatin-taxol; N = 3). Remaining phase II patients received CCB (cyclophosphamide-cisplatin-BCNU).