Clinical characteristics and FISH results of patients with chronic liver disease
| Patient no. . | Age/sex . | Liver histology . | Signs of vasculitis . | Total cell count . | Cells with translocation (%) . |
|---|---|---|---|---|---|
| A1 | 42/F | Mild activity, no fibrosis | Arthritis | 54 | 30 (55) |
| A2 | 58/M | Moderate activity, cirrhosis | Arthritis | 118 | 85 (72) |
| A3 | 46/M | Moderate activity, early cirrhosis | None | 95 | 75 (79) |
| A4 | 37/F | Not done owing to normal ALT | None | 109 | 80 (73) |
| A5 | 62/F | Not done owing to coagulopathy | None | 98 | 3 (3) |
| Clinically advanced cirrhosis with portal hypertension | |||||
| A6 | 60/M | Not done owing to factor XI deficiency | None | 75 | 30 (40) |
| A7 | 61/F | Not done—refusal | Arthritis | 94 | 42 (45) |
| A8 | 54/F | Mild activity, no fibrosis | Arthritis | 85 | 15 (18) |
| A9 | 50/F | No data | No data | 95 | 20 (21) |
| A10 | 39/M | Mild activity, no fibrosis | Skin eruption | 100 | 40 (40) |
| A11 | 60/F | Not done—refusal | Skin eruption | 90 | 50 (71) |
| A12 | 62/F | Moderate to severe activity, septal formation | Skin eruption, arthritis | 78 | 18 (23) |
| A13 | 63/F | Active cirrhosis | Skin eruption | 110 | 45 (41) |
| A14 | 73/F | Not done; clinical cirrhosis, ascites, and portal hypertension | Skin eruption | 78 | 3 (4) |
| A15 | 36/F | Moderate activity, no fibrosis | Glomerulonephritis, skin eruption | 82 | 22 (27) |
| B1 | 50/F | No activity, cirrhosis | — | 112 | 7 (6) |
| B2 | 57/M | Moderate activity, moderate fibrosis | — | 87 | 9 (10) |
| B3 | 54/M | Moderate to severe activity, cirrhosis | — | 57 | 3 (5) |
| B4 | 73/F | Moderate activity, cirrhosis | — | 105 | 5 (5.4) |
| B5 | 70/F | Not done owing to thrombocytopenia | — | 113 | 3 (3) |
| Clinical cirrhosis with portal hypertension | |||||
| B6 | 43/M | Moderate activity, fibrosis | — | 107 | 7 (6) |
| B7 | 69/M | Not done—refusal | — | 113 | 29 (25) |
| B8 | 29/M | Mild activity, minimal fibrosis | — | 89 | 83 (93) |
| B9 | 43/F | Moderate to severe activity, septal fibrosis | — | 86 | 2 (2) |
| B10 | 51/M | Mild activity, moderate fibrosis | — | 77 | 3 (3) |
| B11 | 37/M | Mild activity, fibrosis | — | 104 | 4 (4) |
| B12 | 36/M | Not done | — | 72 | 2 (3) |
| C1 | 25/M | Chronic hepatitis B | — | 118 | 5 (9) |
| C2 | 22/M | Chronic hepatitis B | — | 115 | 5 (4) |
| C3 | 30/M | Chronic hepatitis B, cirrhosis | — | 100 | 3 (3) |
| C4 | 32/M | Chronic hepatitis B | — | 110 | 5 (4.5) |
| C5 | 40/F | Autoimmune hepatitis | — | 111 | 6 (5) |
| C6 | 42/F | Autoimmune hepatitis | — | 123 | 3 (2) |
| C7 | 70/F | PBC | — | 116 | 1 (0.8) |
| Patient no. . | Age/sex . | Liver histology . | Signs of vasculitis . | Total cell count . | Cells with translocation (%) . |
|---|---|---|---|---|---|
| A1 | 42/F | Mild activity, no fibrosis | Arthritis | 54 | 30 (55) |
| A2 | 58/M | Moderate activity, cirrhosis | Arthritis | 118 | 85 (72) |
| A3 | 46/M | Moderate activity, early cirrhosis | None | 95 | 75 (79) |
| A4 | 37/F | Not done owing to normal ALT | None | 109 | 80 (73) |
| A5 | 62/F | Not done owing to coagulopathy | None | 98 | 3 (3) |
| Clinically advanced cirrhosis with portal hypertension | |||||
| A6 | 60/M | Not done owing to factor XI deficiency | None | 75 | 30 (40) |
| A7 | 61/F | Not done—refusal | Arthritis | 94 | 42 (45) |
| A8 | 54/F | Mild activity, no fibrosis | Arthritis | 85 | 15 (18) |
| A9 | 50/F | No data | No data | 95 | 20 (21) |
| A10 | 39/M | Mild activity, no fibrosis | Skin eruption | 100 | 40 (40) |
| A11 | 60/F | Not done—refusal | Skin eruption | 90 | 50 (71) |
| A12 | 62/F | Moderate to severe activity, septal formation | Skin eruption, arthritis | 78 | 18 (23) |
| A13 | 63/F | Active cirrhosis | Skin eruption | 110 | 45 (41) |
| A14 | 73/F | Not done; clinical cirrhosis, ascites, and portal hypertension | Skin eruption | 78 | 3 (4) |
| A15 | 36/F | Moderate activity, no fibrosis | Glomerulonephritis, skin eruption | 82 | 22 (27) |
| B1 | 50/F | No activity, cirrhosis | — | 112 | 7 (6) |
| B2 | 57/M | Moderate activity, moderate fibrosis | — | 87 | 9 (10) |
| B3 | 54/M | Moderate to severe activity, cirrhosis | — | 57 | 3 (5) |
| B4 | 73/F | Moderate activity, cirrhosis | — | 105 | 5 (5.4) |
| B5 | 70/F | Not done owing to thrombocytopenia | — | 113 | 3 (3) |
| Clinical cirrhosis with portal hypertension | |||||
| B6 | 43/M | Moderate activity, fibrosis | — | 107 | 7 (6) |
| B7 | 69/M | Not done—refusal | — | 113 | 29 (25) |
| B8 | 29/M | Mild activity, minimal fibrosis | — | 89 | 83 (93) |
| B9 | 43/F | Moderate to severe activity, septal fibrosis | — | 86 | 2 (2) |
| B10 | 51/M | Mild activity, moderate fibrosis | — | 77 | 3 (3) |
| B11 | 37/M | Mild activity, fibrosis | — | 104 | 4 (4) |
| B12 | 36/M | Not done | — | 72 | 2 (3) |
| C1 | 25/M | Chronic hepatitis B | — | 118 | 5 (9) |
| C2 | 22/M | Chronic hepatitis B | — | 115 | 5 (4) |
| C3 | 30/M | Chronic hepatitis B, cirrhosis | — | 100 | 3 (3) |
| C4 | 32/M | Chronic hepatitis B | — | 110 | 5 (4.5) |
| C5 | 40/F | Autoimmune hepatitis | — | 111 | 6 (5) |
| C6 | 42/F | Autoimmune hepatitis | — | 123 | 3 (2) |
| C7 | 70/F | PBC | — | 116 | 1 (0.8) |