Table 5.

ORs from the prevalences of hemoglobins C and S in severe malaria syndromes among the Dogon

Severe malaria syndromeAC or CCAS
Cerebral manifestations   
 OR (CL) 0.14 (0-0.89) 2.38 (0.24-11.87) 
P .03 .25  
Severe anemia (hct<15%)   
 OR (CL) 0.00 (0-1.76) 0.00 (0-16.09) 
P .23 1  
Hyperparasitemia (Ep>5×105/μL)   
 OR (CL) 0.28 (0.01-1.85) 4.76 (0.47-25.09) 
P .33 .09  
Respiratory distress or shock   
 OR (CL) 0.95 (0.02-8.69) 7.62 (0.15-77.18) 
P .16  
Severe postration   
 OR (CL) 0.00 (0-4.13) 0.00 (0-36.78) 
P .59 
Severe malaria syndromeAC or CCAS
Cerebral manifestations   
 OR (CL) 0.14 (0-0.89) 2.38 (0.24-11.87) 
P .03 .25  
Severe anemia (hct<15%)   
 OR (CL) 0.00 (0-1.76) 0.00 (0-16.09) 
P .23 1  
Hyperparasitemia (Ep>5×105/μL)   
 OR (CL) 0.28 (0.01-1.85) 4.76 (0.47-25.09) 
P .33 .09  
Respiratory distress or shock   
 OR (CL) 0.95 (0.02-8.69) 7.62 (0.15-77.18) 
P .16  
Severe postration   
 OR (CL) 0.00 (0-4.13) 0.00 (0-36.78) 
P .59 

The OR for the AC and CC hemoglobin types, or for the AS hemoglobin type, among severe cases and uncomplicated controls were determined using the chi-square or Fisher exact tests (2×2 tables). Comparisons were not stratified by age. The CL is exact 95%.