Detection of t(11;18)(q21;q21) using interphase FISH with PACs 166G16 and 59N7 in 122 cases of B-cell NHL.
| Diagnosis . | FISH analysis . | Cytogenetic analysis . | ||
|---|---|---|---|---|
| Cases analyzed, no. . | t(11;18)+ cases, no. . | Cases analyzed/abnormal, no. . | t(11;18)− cases, no. . | |
| Extranodal MZBCL of MALT-type | 41 | 8 | 16/6 | 2 |
| Stomach | 24 | 6 | 10/3 | 1 |
| Ileum | 3 | 2* | 1/1 | 1 |
| Colon | 1 | 0 | 1/0 | 0 |
| Parotid | 4 | 0 | 0 | 0 |
| Orbit | 5 | 0 | 2/0 | 0 |
| Cutis | 2 | 0 | 0 | 0 |
| Liver | 1 | 0 | 1/1 | 0 |
| Breast | 1 | 0 | 1/1 | 0 |
| MZBCL | ||||
| Nodal | 19 | 0 | 18/18 | 0 |
| Splenic | 22 | 0 | 12/11 | 0 |
| DLCL | ||||
| Gastric | 10 | 0 | 1/0 | 0 |
| Nodal | 10 | 0 | 10/10 | 0 |
| Hairy cell leukemia | 10 | 0 | 0 | 0 |
| Follicle center cell lymphoma | 10 | 0 | 10/10 | 0 |
| Diagnosis . | FISH analysis . | Cytogenetic analysis . | ||
|---|---|---|---|---|
| Cases analyzed, no. . | t(11;18)+ cases, no. . | Cases analyzed/abnormal, no. . | t(11;18)− cases, no. . | |
| Extranodal MZBCL of MALT-type | 41 | 8 | 16/6 | 2 |
| Stomach | 24 | 6 | 10/3 | 1 |
| Ileum | 3 | 2* | 1/1 | 1 |
| Colon | 1 | 0 | 1/0 | 0 |
| Parotid | 4 | 0 | 0 | 0 |
| Orbit | 5 | 0 | 2/0 | 0 |
| Cutis | 2 | 0 | 0 | 0 |
| Liver | 1 | 0 | 1/1 | 0 |
| Breast | 1 | 0 | 1/1 | 0 |
| MZBCL | ||||
| Nodal | 19 | 0 | 18/18 | 0 |
| Splenic | 22 | 0 | 12/11 | 0 |
| DLCL | ||||
| Gastric | 10 | 0 | 1/0 | 0 |
| Nodal | 10 | 0 | 10/10 | 0 |
| Hairy cell leukemia | 10 | 0 | 0 | 0 |
| Follicle center cell lymphoma | 10 | 0 | 10/10 | 0 |
Indicates that in one of the two cases, an ileum biopsy was analyzed; however, in addition to the ileum, other segments of the gastrointestinal tract were involved by the MALT lymphoma (Table 2, case 6).