Regimens for the eradication of Helicobacter pylori
| Therapy and drug . | Dosage . | Frequency . |
|---|---|---|
| Triple therapy with bismuth subcitrate | ||
| Bismuth | 120 mg | qid for 7 days |
| Tetracycline | 500 mg | qid for 7 days |
| Metronidazole | 500 mg | tid for 7 days |
| Triple therapy with H2-receptor antagonists | ||
| Ranitidine | 300 mg | daily for 6-10 weeks |
| Metronidazole | 500 mg | tid for 12 days |
| Amoxicillin | 750 mg | tid for 12 days |
| Triple therapy with acid-pump inhibitors | ||
| Omeprazole | 20 mg | bid for 7 days |
| Amoxicillin | 1000 mg | bid for 7 days |
| Clarithromycin | 500 mg | bid for 7 days |
| Therapy and drug . | Dosage . | Frequency . |
|---|---|---|
| Triple therapy with bismuth subcitrate | ||
| Bismuth | 120 mg | qid for 7 days |
| Tetracycline | 500 mg | qid for 7 days |
| Metronidazole | 500 mg | tid for 7 days |
| Triple therapy with H2-receptor antagonists | ||
| Ranitidine | 300 mg | daily for 6-10 weeks |
| Metronidazole | 500 mg | tid for 12 days |
| Amoxicillin | 750 mg | tid for 12 days |
| Triple therapy with acid-pump inhibitors | ||
| Omeprazole | 20 mg | bid for 7 days |
| Amoxicillin | 1000 mg | bid for 7 days |
| Clarithromycin | 500 mg | bid for 7 days |
All of these schemes showed eradication rates of about 90%. Any antibiotic regimen that is effective in eradication of H pylorican be used in the initial treatment of MALT lymphoma. Thus far, no regimen has been proven to be superior in inducing lymphoma remissions. A second-line anti-Helicobacter therapy with different antibiotics may be needed in some instances. Patients allergic to penicillin may be given a tetracycline-based regimen.