Competitive binding studies using CCR1/HEK-293 transfected cells
| Radiolabeled ligand . | Competing unlabeled ligand . | IC 50 ± STD nmol/L . |
|---|---|---|
| RANTES | RANTES | 1.17 ± 0.26 |
| RANTES | MIP1β | 7.76 ± 3.04 |
| RANTES | LEC | 11.8 ± 2.77 |
| MIP1α | MIP1α | 5.00 ± 1.75 |
| MIP1α | RANTES | 17.4 ± 1.90 |
| MIP1α | LEC | 24.6 ± 2.85 |
| MIP1β | MIP1β | 29.2 ± 4.00 |
| MIP1β | LEC | 49.1 ± 13.4 |
| Radiolabeled ligand . | Competing unlabeled ligand . | IC 50 ± STD nmol/L . |
|---|---|---|
| RANTES | RANTES | 1.17 ± 0.26 |
| RANTES | MIP1β | 7.76 ± 3.04 |
| RANTES | LEC | 11.8 ± 2.77 |
| MIP1α | MIP1α | 5.00 ± 1.75 |
| MIP1α | RANTES | 17.4 ± 1.90 |
| MIP1α | LEC | 24.6 ± 2.85 |
| MIP1β | MIP1β | 29.2 ± 4.00 |
| MIP1β | LEC | 49.1 ± 13.4 |